Description

2-(4-Piperidinyloxy)-5-(Trifluoromethyl)Pyridinehydrochloride is a high-purity, advanced pharmaceutical intermediate with the CAS number 1219979-10-8. This compound is valued for its role as a critical building block in the synthesis of novel active pharmaceutical ingredients (APIs), particularly in central nervous system (CNS) and oncology research. It is primarily sought by pharmaceutical R&D departments, contract research organizations (CROs), and fine chemical manufacturers engaged in the development of next-generation therapeutics.

Application

• Pharmaceutical Intermediate: A key synthetic precursor in the research and development of new drug candidates.
• CNS Drug Discovery: Used in the synthesis of compounds targeting neurological disorders and psychiatric conditions.
• Oncology Research: Serves as a building block for potential anti-cancer agents and targeted therapies.
• Kinase Inhibitor Development: Integral to creating molecules that modulate kinase activity for various disease pathways.
• Process Chemistry & Scale-Up: Employed in route scouting, optimization, and pilot-scale production for clinical trial material.
• Reference Standard: Used as an analytical standard for quality control and method development in API manufacturing.

Basic Information

Product Name	2-(4-Piperidinyloxy)-5-(Trifluoromethyl)Pyridinehydrochloride
CAS No.	1219979-10-8
Molecular Formula	C11H14ClF3N2O
Molecular Weight	282.69 g/mol
Synonyms	5-(Trifluoromethyl)-2-(4-piperidinyloxy)pyridine hydrochloride; 2-(Piperidin-4-yloxy)-5-(trifluoromethyl)pyridine HCl; 4-((5-(Trifluoromethyl)pyridin-2-yl)oxy)piperidine hydrochloride; 2-(4-Piperidyloxy)-5-trifluoromethylpyridine hydrochloride; 1219979-10-8; 2-Piperidin-4-yloxy-5-trifluoromethyl-pyridine hydrochloride
EINECS	Contact for details

Quality Control

Our 2-(4-Piperidinyloxy)-5-(Trifluoromethyl)Pyridinehydrochloride is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. We provide full traceability and Certificates of Analysis (COA) are available for every shipment, confirming compliance with client specifications and cGMP guidelines for advanced intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to minimize exposure to atmospheric moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Purity (HPLC, Area %)	≥ 99.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.