Description

2-Chloro-6-(3-Methyl-1-Piperidinyl)Pyrazine is a high-purity, advanced pharmaceutical intermediate with a distinct heterocyclic structure. This compound matters for its critical role as a key building block in the synthesis of complex active pharmaceutical ingredients (APIs), particularly in therapeutic areas requiring sophisticated molecular architectures. Pharmaceutical R&D teams and fine chemical manufacturers need this precise intermediate to develop new drug candidates and scale up production processes efficiently and reliably.

Application

• Pharmaceutical Intermediate: A crucial building block in the synthesis of novel drug candidates, particularly for central nervous system (CNS) and antiviral applications.
• Agrochemical Research: Used in the development of new generation pesticides and herbicides, leveraging its pyrazine core for biological activity.
• Ligand Synthesis: Serves as a precursor for creating specialized ligands used in catalysis and material science.
• Chemical Biology Probes: Employed in the design and synthesis of molecular probes for studying enzyme function and biological pathways.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for custom synthesis projects requiring this specific heterocyclic scaffold.

Basic Information

Product Name	2-Chloro-6-(3-Methyl-1-Piperidinyl)Pyrazine
CAS No.	1219967-42-6
Molecular Formula	C10H14ClN3
Molecular Weight	211.69 g/mol
Synonyms	2-Chloro-6-(3-methylpiperidin-1-yl)pyrazine; 6-Chloro-3-(3-methyl-1-piperidinyl)pyrazine; 2-Chloro-6-(3-methyl-1-piperazinyl)pyrazine (common misnomer); Pyrazine, 2-chloro-6-(3-methyl-1-piperidinyl)-; 1219967-42-6; 2-Chloro-6-(3-methylpiperidino)pyrazine
EINECS	Contact for details

Quality Control

Our 2-Chloro-6-(3-Methyl-1-Piperidinyl)Pyrazine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via NMR and mass spectrometry, to ensure it meets the high standards required for pharmaceutical R&D. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.