Description

4-{2-[2-Bromo-4-(sec-Butyl)Phenoxy]-Ethyl}Piperidine Hydrochloride is a high-purity, advanced pharmaceutical intermediate with a complex molecular architecture. This compound matters for its critical role in the synthesis of novel active pharmaceutical ingredients (APIs), particularly in central nervous system (CNS) and receptor-targeted therapeutic research. Pharmaceutical R&D laboratories and fine chemical manufacturers need it as a key building block to develop new drug candidates with potential for improved efficacy and selectivity.

Application

• Pharmaceutical Intermediate: A crucial precursor in the multi-step synthesis of novel drug candidates, especially for neurological and psychiatric disorders.
• Chemical Biology Research: Used as a molecular probe or scaffold in medicinal chemistry for studying receptor-ligand interactions and structure-activity relationships (SAR).
• Active Pharmaceutical Ingredient (API) Development: Serves as a core structural component in the development of new APIs targeting specific G-protein-coupled receptors (GPCRs).
• Process Chemistry & Scale-Up: Employed in process optimization and pilot-scale production for new chemical entities (NCEs) under Good Manufacturing Practice (GMP) conditions.
• Reference Standard: Used as a high-purity analytical standard for quality control and method validation in pharmaceutical analysis.
• Academic & Institutional Research: Facilitates cutting-edge research in synthetic organic chemistry and pharmacology within universities and research institutes.

Basic Information

Product Name	4-{2-[2-Bromo-4-(sec-Butyl)Phenoxy]-Ethyl}Piperidine Hydrochloride
CAS No.	1219956-86-1
Molecular Formula	C17H26BrNO • HCl
Molecular Weight	392.76 g/mol (Free base: 356.30 g/mol)
Synonyms	4-[2-(2-Bromo-4-sec-butylphenoxy)ethyl]piperidine hydrochloride; 2-Bromo-4-sec-butyl-1-[2-(4-piperidinyl)ethoxy]benzene hydrochloride; 1-(2-Bromo-4-sec-butylphenoxy)-2-(4-piperidyl)ethane hydrochloride; 4-(2-(2-Bromo-4-(sec-butyl)phenoxy)ethyl)piperidine HCl; sec-Butyl bromophenoxyethylpiperidine HCl; CAS 1219956-86-1
EINECS	Contact for details

Quality Control

Our 4-{2-[2-Bromo-4-(sec-Butyl)Phenoxy]-Ethyl}Piperidine Hydrochloride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical quality attributes. Our commitment to quality supports compliance with cGMP and ISO standards for pharmaceutical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and light-sensitive; therefore, containers must be kept tightly sealed and under an inert atmosphere (e.g., nitrogen or argon) for long-term storage to prevent degradation. Keep away from heat and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.