Description

4-Benzylpiperazine-2-Carboxylic Acid Hydrochloride is a high-purity, pharmaceutically relevant building block used in the synthesis of complex organic molecules. Its value lies in its role as a key chiral intermediate, enabling the development of novel compounds with potential biological activity. This product is essential for research and development chemists in the pharmaceutical, agrochemical, and fine chemical industries, particularly those focused on creating new active pharmaceutical ingredients (APIs) and specialty chemicals.

Application

• Pharmaceutical Intermediate: A critical chiral building block for the synthesis of novel drug candidates, particularly in central nervous system (CNS) and other therapeutic areas.
• Organic Synthesis Research: Used in academic and industrial R&D for constructing complex piperazine-based heterocycles and peptidomimetics.
• Agrochemical Development: Serves as a precursor in the creation of new crop protection agents and pesticides.
• Ligand and Catalyst Preparation: Employed in the development of chiral ligands for asymmetric catalysis.
• Reference Standard: Utilized as a high-purity analytical standard for quality control and method development in analytical laboratories.

Basic Information

Product Name	4-Benzylpiperazine-2-Carboxylic Acid Hydrochloride
CAS No.	1219423-76-3
Molecular Formula	C12H17ClN2O2
Molecular Weight	256.73 g/mol
Synonyms	4-Benzyl-2-piperazinecarboxylic acid hydrochloride; (S)-4-Benzyl-2-piperazinecarboxylic acid hydrochloride; (S)-4-Benzylpiperazine-2-carboxylic acid hydrochloride; 4-Bzl-Pip(2)-OH·HCl; 4-Benzyl-2-carboxypiperazine hydrochloride; 2-Carboxy-4-benzylpiperazine hydrochloride; 1-Benzyl-3-carboxypiperazine hydrochloride; 4-Benzylpiperazine-2-carboxylic acid HCl salt
EINECS	Contact for details

Quality Control

Our 4-Benzylpiperazine-2-Carboxylic Acid Hydrochloride is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity verification, to ensure it meets the high standards required for pharmaceutical research and development. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and must be kept under anhydrous conditions. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Assay (HPLC)	≥98.0%
Chiral Purity (Chiral HPLC)	≥99.0% ee
Water Content (KF)	≤0.5%
Residue on Ignition	≤0.1%
Heavy Metals	≤10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.