Description

tert-Butyl 3-((Methoxycarbonyl)(Amino)Methyl)Piperidine-1-Carboxylate CAS NO 1219380-30-9 is a sophisticated, high-purity chemical intermediate featuring a protected piperidine scaffold. This compound is critical for pharmaceutical research and development, serving as a versatile building block for the synthesis of novel active pharmaceutical ingredients (APIs). It is primarily utilized by medicinal chemists and process development scientists in the pharmaceutical and biotechnology industries to construct complex molecular architectures with potential therapeutic value.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of complex drug candidates, particularly those targeting the central nervous system (CNS) and other therapeutic areas.
• Medicinal Chemistry Research: Used in lead optimization and structure-activity relationship (SAR) studies to develop new pharmacologically active molecules.
• Process Chemistry Development: Serves as a starting material or intermediate in scaling up synthetic routes for API manufacturing under Good Manufacturing Practice (GMP) conditions.
• Protease Inhibitor Synthesis: The structural motif is valuable in constructing inhibitors for various protease enzymes, a significant class of drug targets.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for the production of bespoke compounds for clinical trials.
• Academic Research: Employed in university and institutional labs for methodological development and exploratory synthesis in organic and medicinal chemistry.

Basic Information

Product Name	tert-Butyl 3-((Methoxycarbonyl)(Amino)Methyl)Piperidine-1-Carboxylate
CAS No.	1219380-30-9
Molecular Formula	C14H26N2O4
Molecular Weight	286.37 g/mol
Synonyms	1-Boc-3-[(Methoxycarbonyl)(Amino)Methyl]Piperidine; 1-(tert-Butoxycarbonyl)-3-[(Methoxycarbonyl)(Amino)Methyl]Piperidine; tert-Butyl 3-[(Methoxycarbonyl)(Amino)Methyl]-1-piperidinecarboxylate; 3-[(Methoxycarbonyl)(Amino)Methyl]Piperidine-1-carboxylic Acid tert-Butyl Ester; 1-Boc-3-[(Methoxycarbonyl)(Amino)Methyl]Piperidine; Boc-3-[(Methoxycarbonyl)(Amino)Methyl]Piperidine; N-Boc-3-[(Methoxycarbonyl)(Amino)Methyl]Piperidine; 3-(Amino(methoxycarbonyl)methyl)piperidine-1-carboxylic acid tert-butyl ester
EINECS	Contact for details

Quality Control

Our tert-Butyl 3-((Methoxycarbonyl)(Amino)Methyl)Piperidine-1-Carboxylate is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity suitable for research and development. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We adhere to relevant quality management standards, and specifications can be aligned with customer requirements for advanced pharmaceutical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.