Description

5-Phenyl-Piperidine-1,2-Dicarboxylic Acid 1-tert-Butyl Ester is a high-purity, advanced pharmaceutical intermediate of significant importance in modern organic synthesis. Its value lies in its role as a critical building block for constructing complex molecules, particularly in medicinal chemistry and drug discovery pipelines. This compound is essential for research and development chemists in the pharmaceutical, agrochemical, and fine chemical industries who require reliable, high-quality intermediates for the synthesis of novel active compounds.

Application

• Pharmaceutical Intermediate: A key chiral building block in the synthesis of potential drug candidates, particularly those targeting the central nervous system (CNS).
• Medicinal Chemistry Research: Used in the research and development of new chemical entities (NCEs) and for structure-activity relationship (SAR) studies.
• Peptidomimetic Synthesis: Serves as a constrained scaffold for designing and synthesizing peptide mimics with enhanced metabolic stability.
• Agrochemical Development: Employed in the synthesis of novel, high-performance active ingredients for crop protection.
• Catalyst and Ligand Preparation: Utilized as a precursor for synthesizing specialized chiral catalysts and ligands used in asymmetric synthesis.
• Academic and Institutional R&D: A valuable reagent for universities and research institutes conducting advanced organic and synthetic chemistry projects.

Basic Information

Product Name	5-Phenyl-Piperidine-1,2-Dicarboxylic Acid 1-tert-Butyl Ester
CAS No.	1219369-17-1
Molecular Formula	C18H25NO4
Molecular Weight	319.40 g/mol
Synonyms	1-(tert-Butyl) 2-(5-phenylpiperidine-1,2-dicarboxylate); 5-Phenylpiperidine-1,2-dicarboxylic acid 1-tert-butyl ester; 1-tert-Butyl 5-phenylpiperidine-1,2-dicarboxylate; tert-Butyl 5-phenyl-1,2-piperidinedicarboxylate; 5-Phenyl-1,2-piperidinedicarboxylic acid 1-(1,1-dimethylethyl) ester; (2S)-1-tert-Butoxycarbonyl-5-phenylpiperidine-2-carboxylic acid (if chiral); BOC-5-Phenyl-piperidine-2-carboxylic acid derivative
EINECS	Contact for details

Quality Control

Our production of 5-Phenyl-Piperidine-1,2-Dicarboxylic Acid 1-tert-Butyl Ester adheres to stringent quality management protocols to ensure batch-to-batch consistency and high purity. Each lot undergoes comprehensive analytical testing, including HPLC, NMR, and MS, to confirm identity and purity. A Certificate of Analysis (COA) detailing all specifications is provided with every shipment. We operate under a quality system designed to meet the rigorous standards required by our global pharmaceutical and research clients.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). The compound may be hygroscopic (moisture-sensitive); keep the container tightly sealed under an inert atmosphere if necessary for long-term storage.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.