Description

tert-Butyl4-(Pyrrolidine-2-Carbonyl)Piperazine-1-Carboxylate (Wxc08046) is a high-purity, protected piperazine-pyrrolidine hybrid building block of significant interest in advanced organic synthesis. This compound is specifically engineered to serve as a critical intermediate in the development of novel, complex molecules, offering a versatile scaffold for medicinal chemistry and drug discovery. It is primarily targeted at research and development teams within the pharmaceutical, agrochemical, and fine chemical industries seeking to create new active ingredients with enhanced properties.

Application

• Pharmaceutical Intermediate: A key building block for the synthesis of potential drug candidates, particularly in the development of protease inhibitors, kinase inhibitors, and other small-molecule therapeutics.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization to introduce the piperazine-pyrrolidine motif, which is common in bioactive molecules.
• Agrochemical Synthesis: Serves as a precursor in the development of novel pesticides and herbicides, where its structural features can contribute to biological activity.
• Chemical Biology Probes: Utilized in the creation of molecular probes for studying enzyme function and biological pathways.
• Peptidomimetics Development: Acts as a core scaffold for designing peptidomimetic compounds that mimic the structure and function of natural peptides.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs and research organizations for use in custom synthesis projects and scale-up campaigns.

Basic Information

Product Name	tert-Butyl4-(Pyrrolidine-2-Carbonyl)Piperazine-1-Carboxylate (Wxc08046)
CAS No.	1219201-40-7
Molecular Formula	C14H25N3O3
Molecular Weight	283.37 g/mol
Synonyms	1-Boc-4-(L-prolyl)piperazine; tert-Butyl 4-(pyrrolidine-2-carbonyl)piperazine-1-carboxylate; 1-(tert-Butoxycarbonyl)-4-(2-pyrrolidinecarbonyl)piperazine; 4-(Pyrrolidine-2-carbonyl)piperazine-1-carboxylic acid tert-butyl ester; WXC-08046; Wxc08046; (S)-tert-Butyl 4-(pyrrolidine-2-carbonyl)piperazine-1-carboxylate; 1-Boc-4-(L-prolyl)piperazine
EINECS	Contact for details

Quality Control

Our tert-Butyl4-(Pyrrolidine-2-Carbonyl)Piperazine-1-Carboxylate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity, chiral analysis, and NMR/IR for structural confirmation, to ensure it meets the high standards required for research and development applications. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are provided with every shipment and are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under dry, inert conditions to maintain stability and purity. For long-term storage, consider storing under an inert atmosphere such as nitrogen or argon.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Chiral Purity	≥ 98.0% ee
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.