Description

6-Phenyl-Piperidine-2-Carboxylic Acid is a high-purity, synthetically versatile piperidine derivative. This compound serves as a critical chiral building block and intermediate in advanced organic synthesis, valued for its structural rigidity and functional handles. It is primarily utilized by research and development chemists in the pharmaceutical and agrochemical industries for the creation of novel active ingredients and complex molecular architectures.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the research and development of new drug candidates, particularly for central nervous system (CNS) and metabolic disorder targets.
• Agrochemical Synthesis: Used in the development of advanced pesticides and herbicides, where the piperidine scaffold contributes to biological activity.
• Ligand and Catalyst Development: Serves as a precursor for chiral ligands and organocatalysts used in asymmetric synthesis.
• Chemical Research: Employed in academic and industrial R&D for exploring novel heterocyclic chemistry and structure-activity relationships (SAR).
• Peptidomimetics: The carboxylic acid functionality allows for incorporation into peptide backbones to create modified peptides with enhanced stability or activity.

Basic Information

Product Name	6-Phenyl-Piperidine-2-Carboxylic Acid
CAS No.	1219143-12-0
Molecular Formula	C12H15NO2
Molecular Weight	205.25 g/mol
Synonyms	2-Carboxy-6-phenylpiperidine; 6-Phenyl-2-piperidinecarboxylic acid; 6-Phenylpipecolic Acid; (2S)-6-Phenylpiperidine-2-carboxylic acid (for enantiopure forms); 6-Phenyl-DL-pipecolic acid; 2-Piperidinecarboxylic acid, 6-phenyl-; 6-Phenyl-2-carboxypiperidine
EINECS	Contact for details

Quality Control

Our 6-Phenyl-Piperidine-2-Carboxylic Acid is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, chiral analysis, and identity confirmation, to ensure it meets the high standards required for research and synthesis. Certificates of Analysis (COA) with detailed chromatographic data are provided for every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). Keep away from strong acids and organic solvents. For long-term storage, consider inert atmosphere conditions to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.