Description

Ethyl 2-(7-Iodo-1-Oxo-1,2,3,4-Tetrahydropyrrolo[1,2-A]Pyrazin-4-Yl)Acetate is a high-value, heterocyclic organic compound featuring a fused pyrrolopyrazine core with an iodine substituent and an ester functional group. This specific molecular architecture makes it a critical pharmaceutical intermediate and a versatile building block for medicinal chemistry research. It is primarily sought after by R&D teams in the pharmaceutical and biotechnology sectors for the synthesis of novel drug candidates. The compound's unique structure allows for further functionalization, enabling the exploration of new chemical space in drug discovery programs.

Application

• Pharmaceutical Intermediate: A key synthetic precursor in the development of active pharmaceutical ingredients (APIs), particularly for central nervous system (CNS) and oncology targets.
• Medicinal Chemistry Research: Serves as a versatile scaffold for structure-activity relationship (SAR) studies and the creation of focused compound libraries.
• Organic Synthesis Building Block: Used in cross-coupling reactions (e.g., Suzuki, Sonogashira) facilitated by the iodine atom, and further transformations of the ester group.
• Chemical Biology Probes: Potential use in the development of molecular probes for studying biological pathways and target engagement.
• Contract Research & Manufacturing (CRO/CMO): Supplied to organizations specializing in custom synthesis and process development for the pharmaceutical industry.

Basic Information

Product Name	Ethyl 2-(7-Iodo-1-Oxo-1,2,3,4-Tetrahydropyrrolo[1,2-A]Pyrazin-4-Yl)Acetate
CAS No.	1218810-48-0
Molecular Formula	C₁₂H₁₃IN₂O₃
Molecular Weight	360.15 g/mol
Synonyms	Ethyl (7-iodo-1-oxo-1,2,3,4-tetrahydropyrrolo[1,2-a]pyrazin-4-yl)acetate; 4-(Ethoxycarbonylmethyl)-7-iodo-3,4-dihydro-1H-pyrrolo[1,2-a]pyrazin-1-one; 7-Iodo-4-(2-ethoxy-2-oxoethyl)-3,4-dihydro-1H-pyrrolo[1,2-a]pyrazin-1-one; 1218810-48-0; Pyrrolo[1,2-a]pyrazine-1-one, 4-(2-ethoxy-2-oxoethyl)-7-iodo-3,4-dihydro-; SCHEMBL21806227; BDBM50389355; AKOS025147310
EINECS	Contact for details

Quality Control

Our production of Ethyl 2-(7-Iodo-1-Oxo-1,2,3,4-Tetrahydropyrrolo[1,2-A]Pyrazin-4-Yl)Acetate adheres to stringent quality protocols suitable for research and pharmaceutical intermediate applications. Each batch is characterized and tested using advanced analytical techniques including HPLC, NMR, and MS to ensure identity, purity, and consistency. Certificates of Analysis (COA) with detailed chromatographic and spectroscopic data are provided to support your R&D and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (typically 15-25°C). The compound may be light-sensitive and should be handled under inert atmosphere for long-term storage to ensure stability.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.