Description

(1S,4S)-2-Benzyl-2,5-Diazabicyclo[2.2.1]Heptane-2Hcl CAS NO 1217827-86-5 is a high-purity, chiral bicyclic diamine derivative, serving as a critical pharmaceutical intermediate and organocatalyst precursor. Its rigid, three-dimensional structure makes it invaluable for constructing complex molecular architectures with precise stereochemical control. This compound is essential for R&D and production teams in pharmaceutical development, asymmetric synthesis, and advanced material science.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of active pharmaceutical ingredients (APIs), particularly in neurology and oncology drug candidates.
• Chiral Ligand & Catalyst: Used in asymmetric catalysis for the enantioselective synthesis of fine chemicals and agrochemicals.
• Organic Synthesis Reagent: Employed in the construction of complex nitrogen-containing heterocycles and natural product analogs.
• Chemical Biology Probe: Serves as a scaffold for developing enzyme inhibitors and molecular probes in biochemical research.
• Material Science: Potential precursor for functional polymers and metal-organic frameworks (MOFs) with specific chiral properties.

Basic Information

Product Name	(1S,4S)-2-Benzyl-2,5-Diazabicyclo[2.2.1]Heptane Dihydrochloride
CAS No.	1217827-86-5
Molecular Formula	C₁₂H₁₈Cl₂N₂
Molecular Weight	261.19 g/mol
Synonyms	(1S,4S)-2-Benzyl-2,5-diazabicyclo[2.2.1]heptane dihydrochloride; 2-Benzyl-2,5-diazabicyclo[2.2.1]heptane hydrochloride (1S,4S)-; (1S,4S)-2-Benzyl-2,5-diazabicyclo[2.2.1]heptane 2HCl; endo-2-Benzyl-2,5-diazabicyclo[2.2.1]heptane dihydrochloride; Bn-DABCO-HCl (chiral derivative); 2-Benzyl-1,4-diazabicyclo[2.2.1]heptane dihydrochloride
EINECS	Contact for details

Quality Control

Our (1S,4S)-2-Benzyl-2,5-Diazabicyclo[2.2.1]Heptane-2Hcl is manufactured under strict quality systems. Each batch undergoes rigorous analytical testing to ensure high chemical purity and chiral integrity, meeting the stringent requirements for pharmaceutical R&D. Certificates of Analysis (COA) with detailed chromatographic and spectroscopic data are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to prevent moisture absorption, which can affect stability and handling properties.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.