Description

(S)-Benzyl 3-Methylpiperazine-1-Carboxylate Hydrochloride CAS NO 1217812-89-9 is a high-purity chiral piperazine derivative, a critical building block in modern pharmaceutical synthesis. Its value lies in providing a stereochemically defined scaffold essential for developing active pharmaceutical ingredients (APIs) with targeted biological activity. This intermediate is primarily needed by research institutions and pharmaceutical companies engaged in the discovery and process development of new therapeutic agents, particularly in oncology and central nervous system (CNS) drug discovery.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the multi-step synthesis of novel drug candidates, especially those targeting specific receptors.
• API Development: Serves as a core structural component in the research and process chemistry for new Active Pharmaceutical Ingredients (APIs).
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies to optimize the potency and selectivity of lead compounds.
• Asymmetric Synthesis: Employed in reactions requiring a chiral piperazine moiety to induce stereoselectivity in the final molecule.
• Contract Manufacturing (CMO): Supplied to contract research and manufacturing organizations (CROs/CMOs) for custom synthesis projects.
• Preclinical & Clinical Trial Material: Used to produce batches of investigational compounds for preclinical testing and early-phase clinical trials.

Basic Information

Product Name	(S)-Benzyl 3-Methylpiperazine-1-Carboxylate Hydrochloride
CAS No.	1217812-89-9
Molecular Formula	C14H21ClN2O2
Molecular Weight	284.78 g/mol
Synonyms	(S)-Benzyl 3-Methylpiperazine-1-carboxylate HCl; (S)-1-Benzyloxycarbonyl-3-methylpiperazine hydrochloride; (S)-Cbz-3-Methylpiperazine Hydrochloride; (S)-N-Cbz-3-Methylpiperazine HCl; (3S)-1-[(Benzyloxy)carbonyl]-3-methylpiperazine hydrochloride; (S)-1-(Benzyloxycarbonyl)-3-methylpiperazine hydrochloride; (S)-3-Methyl-1-(phenylmethoxy)carbonylpiperazine hydrochloride
EINECS	Contact for details

Quality Control

Our (S)-Benzyl 3-Methylpiperazine-1-Carboxylate Hydrochloride is manufactured under strict quality systems to ensure batch-to-batch consistency and high purity, suitable for advanced synthetic applications. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, chiral purity, and impurity profiles. We adhere to cGMP principles where applicable to support our clients' regulatory requirements for pharmaceutical development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive); the container must be kept tightly sealed to prevent exposure to atmospheric moisture, which can affect stability and handling properties.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥98.0%
Chiral Purity (Chiral HPLC)	≥99.0% ee
Water Content (KF)	≤0.5%
Residue on Ignition	≤0.1%
Heavy Metals	≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.