Description

(S)-4-n-Cbz-2-Ethylpiperazine-Hcl CAS NO 1217764-12-9 is a high-purity chiral piperazine derivative, serving as a critical pharmaceutical intermediate and building block in advanced organic synthesis. Its value lies in providing a stereochemically defined scaffold for constructing complex molecules with targeted biological activity. This compound is essential for research and development chemists in the pharmaceutical and biotechnology sectors, particularly for the synthesis of active pharmaceutical ingredients (APIs), drug candidates, and specialized fine chemicals.

Application

• Pharmaceutical Intermediate: Key chiral building block for the synthesis of novel drug candidates, particularly in central nervous system (CNS) and oncology research.
• API Synthesis: Used in the construction of complex Active Pharmaceutical Ingredients (APIs) requiring a specific (S)-configured piperazine core.
• Medicinal Chemistry Research: A versatile scaffold for structure-activity relationship (SAR) studies and library synthesis in drug discovery programs.
• Asymmetric Synthesis: Employed as a chiral auxiliary or ligand precursor in catalytic asymmetric reactions.
• Peptidomimetics: Integration into peptide-like structures to enhance metabolic stability and bioavailability.
• Fine Chemical Production: Intermediate for the manufacture of high-value specialty chemicals and advanced materials.

Basic Information

Product Name	(S)-4-n-Cbz-2-Ethylpiperazine-Hcl
CAS No.	1217764-12-9
Molecular Formula	C14H21N3O2 • HCl
Molecular Weight	299.80 g/mol
Synonyms	(S)-1-(Benzyloxycarbonyl)-4-ethylpiperazine-2-carboxylic acid hydrochloride; (S)-1-Cbz-4-ethylpiperazine-2-carboxylic acid HCl; (S)-4-(Carbobenzyloxy)-2-ethylpiperazine hydrochloride; (S)-N-Carbobenzyloxy-4-ethylpiperazine-2-carboxylic acid hydrochloride; (2S)-1-[(Benzyloxy)carbonyl]-4-ethylpiperazine-2-carboxylic acid hydrochloride; (S)-1-Cbz-4-Et-piperazine-2-COOH • HCl; (S)-4-Ethyl-1-[(phenylmethoxy)carbonyl]piperazine-2-carboxylic acid hydrochloride
EINECS	Contact for details

Quality Control

Our (S)-4-n-Cbz-2-Ethylpiperazine-Hcl is produced under strict quality management systems to ensure batch-to-batch consistency and high purity. Each lot undergoes comprehensive analytical testing, including HPLC for purity and chiral integrity, NMR for structural confirmation, and residual solvent analysis. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting all critical quality attributes to support your regulatory and R&D requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive); therefore, containers must be kept tightly sealed and consideration should be given to storage under an inert atmosphere for long-term preservation of quality.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.