Description

(trans-Racemic)-1-tert-Butyl 3-Methyl 4-(5-Bromo-3-Methoxypyridin-2-Yl)Pyrrolidine-1,3-Dicarboxylate is a high-purity, advanced pharmaceutical intermediate designed for complex synthesis pathways. This compound is critical for research and development in medicinal chemistry, particularly in the construction of novel active pharmaceutical ingredients (APIs). It is primarily utilized by pharmaceutical R&D laboratories and fine chemical manufacturers specializing in small molecule drug discovery and process development.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of complex drug candidates, particularly those targeting the central nervous system (CNS) and oncology.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization programs to explore new chemical entities.
• Process Chemistry Development: Serves as a critical starting material or intermediate in scaling up synthetic routes for preclinical and clinical trial material production.
• Contract Research & Manufacturing (CRO/CMO): Supplied to organizations providing custom synthesis and development services for the global pharmaceutical industry.
• Academic Research: Employed in university and institutional labs for cutting-edge research in organic synthesis and heterocyclic chemistry.

Basic Information

Product Name	(trans-Racemic)-1-tert-Butyl 3-Methyl 4-(5-Bromo-3-Methoxypyridin-2-Yl)Pyrrolidine-1,3-Dicarboxylate
CAS No.	1217743-30-0
Molecular Formula	C18H25BrN2O5
Molecular Weight	429.31 g/mol
Synonyms	1-(tert-Butoxycarbonyl)-3-(methoxycarbonyl)-4-(5-bromo-3-methoxypyridin-2-yl)pyrrolidine; 4-(5-Bromo-3-methoxypyridin-2-yl)-1-(tert-butoxycarbonyl)-3-(methoxycarbonyl)pyrrolidine; 1-Boc-3-methyl 4-(5-bromo-3-methoxypyridin-2-yl)pyrrolidine-1,3-dicarboxylate; trans-1-tert-Butyl 3-methyl 4-(5-bromo-3-methoxypyridin-2-yl)pyrrolidine-1,3-dicarboxylate; (trans)-1-tert-Butyl 3-methyl 4-(5-bromo-3-methoxypyridin-2-yl)pyrrolidine-1,3-dicarboxylate; (trans)-1-Boc-3-methyl 4-(5-bromo-3-methoxypyridin-2-yl)pyrrolidine-1,3-dicarboxylate; 1217743-30-0; 4-(5-Bromo-3-methoxypyridin-2-yl)pyrrolidine-1,3-dicarboxylic acid 1-tert-butyl ester 3-methyl ester
EINECS	Contact for details

Quality Control

Our products undergo rigorous quality testing to ensure compliance with industry standards for pharmaceutical intermediates. Every batch is analyzed using advanced techniques like HPLC, GC, and NMR to confirm identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are available upon request, supporting your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 97.0%
Related Substances (HPLC)	Any single impurity ≤ 1.0%; Total impurities ≤ 3.0%
Residual Solvents (GC)	Complies with ICH Q3C guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.