Description

1-Piperidinecarboxylic Acid, 2-(1-Methylethyl)-4-Oxo-, 1,1-Dimethylethyl Ester, (2S)- is a high-purity, chiral piperidine derivative serving as a critical building block in advanced organic synthesis. Its value lies in its role as a sophisticated intermediate for constructing complex molecules with defined stereochemistry, enabling the development of novel active pharmaceutical ingredients (APIs). This compound is essential for research and development chemists and process scale-up teams in the pharmaceutical, agrochemical, and fine chemical industries who require reliable access to high-quality, stereochemically pure intermediates.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the research and development of new therapeutic agents, particularly for central nervous system (CNS) and metabolic disorder targets.
• Agrochemical Synthesis: Used in the production of advanced crop protection agents where specific stereochemistry is crucial for biological activity.
• Catalyst and Ligand Development: Serves as a precursor for creating novel chiral catalysts and ligands used in asymmetric synthesis.
• Fine Chemical Manufacturing: Employed in the custom synthesis of complex, high-value specialty chemicals for various industrial applications.
• Academic and R&D Laboratories: A valuable compound for methodological studies in organic chemistry and medicinal chemistry research programs.

Basic Information

Product Name	1-Piperidinecarboxylic Acid, 2-(1-Methylethyl)-4-Oxo-, 1,1-Dimethylethyl Ester, (2S)-
CAS No.	1217732-08-5
Molecular Formula	C13H23NO3
Molecular Weight	241.33 g/mol
Synonyms	(2S)-2-Isopropyl-4-oxo-1-piperidinecarboxylic acid tert-butyl ester; tert-Butyl (2S)-2-isopropyl-4-oxopiperidine-1-carboxylate; (S)-tert-Butyl 2-isopropyl-4-oxopiperidine-1-carboxylate; (S)-Boc-2-isopropyl-4-oxopiperidine; (2S)-Boc-2-isopropyl-4-piperidone; 1-Boc-4-oxo-(S)-2-isopropylpiperidine; 1-(tert-Butoxycarbonyl)-4-oxo-(S)-2-isopropylpiperidine
EINECS	Contact for details

Quality Control

Our production of this chiral intermediate adheres to strict quality management systems to ensure batch-to-batch consistency and high chemical purity. Each lot is characterized using advanced analytical techniques including HPLC, GC, NMR, and chiral analysis to confirm identity, purity, and enantiomeric excess. Certificates of Analysis (COA) detailing all relevant specifications are provided with every shipment. We support development under cGMP guidelines as required for pharmaceutical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). Keep away from heat, sparks, and open flame. The container should be kept tightly sealed to protect from moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.