Description

(S)-1-n-Boc-2-Methoxymethylpiperazine is a high-purity, chiral piperazine derivative that serves as a critical building block in modern organic synthesis. This compound matters because it provides a protected, stereochemically defined scaffold essential for constructing complex molecules with high enantiomeric purity. Pharmaceutical and agrochemical R&D teams need it for the development of active pharmaceutical ingredients (APIs), catalysts, and advanced intermediates, where precise stereochemistry is non-negotiable.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the synthesis of protease inhibitors, kinase inhibitors, and other small-molecule therapeutics.
• Agrochemical Synthesis: Used in the research and development of enantiomerically pure herbicides, fungicides, and plant growth regulators.
• Catalyst & Ligand Preparation: Serves as a precursor for chiral ligands and organocatalysts used in asymmetric synthesis.
• Peptidomimetics & Macrocyclic Compounds: Integral for constructing constrained peptide analogs and macrocyclic scaffolds in drug discovery.
• Custom Chemical Synthesis: Employed by contract research and manufacturing organizations (CROs/CMOs) for bespoke synthesis projects.
• Academic & Industrial Research: A valuable reagent for methodological development in organic chemistry and medicinal chemistry programs.

Basic Information

Product Name	(S)-1-n-Boc-2-Methoxymethylpiperazine
CAS No.	1217728-72-7
Molecular Formula	C12H24N2O3
Molecular Weight	244.33 g/mol
Synonyms	1-Boc-2-(methoxymethyl)-(S)-piperazine; (S)-1-(tert-Butoxycarbonyl)-2-(methoxymethyl)piperazine; tert-Butyl (S)-2-(methoxymethyl)piperazine-1-carboxylate; (S)-2-(Methoxymethyl)-1-(tert-butoxycarbonyl)piperazine; (S)-N-Boc-2-methoxymethylpiperazine; 1-N-BOC-2-METHOXYMETHYL-(S)-PIPERAZINE; (S)-1-Boc-2-methoxymethylpiperazine; BOC-(S)-2-Methoxymethylpiperazine
EINECS	Contact for details

Quality Control

Our (S)-1-n-Boc-2-Methoxymethylpiperazine is manufactured under strict quality management systems to ensure batch-to-batch consistency and high chemical purity. Each lot undergoes comprehensive analytical testing, including chiral HPLC for enantiomeric excess (ee) verification, to meet the stringent requirements of pharmaceutical development. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.