Description

(S)-2-Amino-3-Methyl-1-(4-Methyl-Piperazin-1-Yl)-Butan-1-One is a high-purity chiral intermediate featuring a unique piperazine-substituted amino ketone structure. This compound is of significant value for its role in the synthesis of complex, biologically active molecules, offering precise stereochemical control. It is primarily sought after by research institutions and pharmaceutical companies engaged in the development of novel therapeutic agents, including potential central nervous system (CNS) drugs and enzyme inhibitors.

Application

• Pharmaceutical Intermediate: A key chiral building block for the research and development of new active pharmaceutical ingredients (APIs).
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization for drug discovery programs.
• Peptidomimetic Synthesis: Serves as a precursor for synthesizing peptide analogs and mimetics due to its amino ketone functionality.
• Asymmetric Synthesis: Employed as a chiral auxiliary or starting material in stereoselective chemical transformations.
• Bioconjugation & Probe Development: Potential use in creating labeled compounds or molecular probes for biochemical assays.

Basic Information

Product Name	(S)-2-Amino-3-Methyl-1-(4-Methyl-Piperazin-1-Yl)-Butan-1-One
CAS No.	1217695-67-4
Molecular Formula	C10H21N3O
Molecular Weight	199.30 g/mol
Synonyms	1-(4-Methylpiperazin-1-yl)-3-methyl-2-aminobutan-1-one (S-isomer); (S)-1-(4-Methyl-1-piperazinyl)-3-methyl-2-aminobutan-1-one; (S)-2-Amino-3-methyl-1-(4-methylpiperazin-1-yl)butan-1-one; (S)-α-Amino-β-methyl-1-(4-methylpiperazinyl)butyrophenone (analogous naming); (S)-Amino Methyl Piperazinyl Butanone; CAS 1217695-67-4; Chiral Piperazine Amino Ketone Intermediate
EINECS	Contact for details

Quality Control

Our (S)-2-Amino-3-Methyl-1-(4-Methyl-Piperazin-1-Yl)-Butan-1-One is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity verification by HPLC, to ensure compliance with high-purity standards for research and development. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under dry conditions to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.