Description

cis-4-Boc-Amino-Piperidine-3-Carboxylic Acid Methyl Ester is a high-purity, protected amino acid derivative of significant value in advanced organic synthesis. This compound serves as a critical chiral building block and versatile synthetic intermediate for the construction of complex molecular architectures. It is primarily needed by research institutions and pharmaceutical companies engaged in the development of novel active pharmaceutical ingredients (APIs), peptidomimetics, and other bioactive compounds.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the research and development of new drug candidates, particularly for central nervous system (CNS) and metabolic disorder targets.
• Peptidomimetic Synthesis: Used to introduce constrained, functionalized piperidine scaffolds into peptide backbones to enhance metabolic stability and bioavailability.
• Chemical Biology & Proteomics: Employed in the synthesis of specialized probes, inhibitors, and ligands for studying enzyme function and protein-protein interactions.
• Custom Synthesis & Contract Manufacturing: Serves as a starting material for custom synthesis services, supporting the production of complex molecules on laboratory to pilot scale.
• Academic & Industrial Research: Utilized in methodological development and the synthesis of novel chemical libraries for high-throughput screening.

Basic Information

Product Name	cis-4-Boc-Amino-Piperidine-3-Carboxylic Acid Methyl Ester
CAS No.	1217684-50-8
Molecular Formula	C13H24N2O4
Molecular Weight	272.34 g/mol
Synonyms	Methyl (3R,4S)-1-tert-Butoxycarbonyl-4-aminopiperidine-3-carboxylate; (3R,4S)-1-Boc-4-Aminopiperidine-3-carboxylic Acid Methyl Ester; cis-4-[(tert-Butoxycarbonyl)amino]piperidine-3-carboxylic Acid Methyl Ester; 1-Boc-cis-4-amino-3-piperidinecarboxylic Acid Methyl Ester; 1-N-Boc-cis-4-amino-3-piperidinecarboxylic Acid Methyl Ester; Methyl 1-Boc-cis-4-amino-3-piperidinecarboxylate; cis-4-(Boc-amino)piperidine-3-carboxylic Acid Methyl Ester
EINECS	Contact for details

Quality Control

Our cis-4-Boc-Amino-Piperidine-3-Carboxylic Acid Methyl Ester is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity verification, to ensure it meets the high standards required for pharmaceutical research and development. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to prevent moisture absorption, which may affect product stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.