Description

(R)-3-Methoxycarbonylmethyl-Piperazine-1-Carboxylic Acid tert-Butyl Ester CAS NO 1217683-44-7 is a high-purity chiral piperazine derivative, serving as a critical building block in advanced organic synthesis. Its primary value lies in providing a stereochemically defined scaffold for constructing complex molecules, enabling precise control over the final product's biological activity. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, particularly in the development of novel active pharmaceutical ingredients (APIs) and fine chemicals.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the research and development of new therapeutic agents, including central nervous system (CNS) drugs and enzyme inhibitors.
• Agrochemical Synthesis: Used in the creation of advanced, stereoselective pesticides and herbicides where specific chirality enhances efficacy and reduces environmental impact.
• Asymmetric Catalysis Ligand Precursor: Serves as a starting material for synthesizing chiral ligands used in asymmetric hydrogenation and other catalytic processes.
• Peptidomimetics Research: Employed in medicinal chemistry to construct constrained peptide analogs and protease inhibitors.
• Custom Chemical Synthesis: A versatile building block for contract research organizations (CROs) and CDMOs producing bespoke compounds for client projects.
• Academic & Institutional Research: Used in university and institutional labs for methodological studies in organic chemistry and drug discovery programs.

Basic Information

Product Name	(R)-3-Methoxycarbonylmethyl-Piperazine-1-Carboxylic Acid tert-Butyl Ester
CAS No.	1217683-44-7
Molecular Formula	C13H24N2O4
Molecular Weight	272.34 g/mol
Synonyms	(R)-1-Boc-3-(methoxycarbonylmethyl)piperazine; (R)-1-(tert-Butoxycarbonyl)-3-(methoxycarbonylmethyl)piperazine; (R)-3-(Methoxycarbonylmethyl)-1-Boc-piperazine; tert-Butyl (R)-3-(methoxycarbonylmethyl)piperazine-1-carboxylate; (R)-1-Boc-3-carbomethoxymethylpiperazine; (R)-3-(Carbomethoxymethyl)-1-Boc-piperazine; (R)-N-Boc-3-(methoxycarbonylmethyl)piperazine; (R)-3-Methoxycarbonylmethyl-1-Boc-piperazine
EINECS	Contact for details

Quality Control

Our (R)-3-Methoxycarbonylmethyl-Piperazine-1-Carboxylic Acid tert-Butyl Ester is manufactured under strict quality management systems. We provide material that meets high-purity standards suitable for pharmaceutical research and development. Certificates of Analysis (COA) are available for every batch, detailing purity, chiral purity, and impurity profiles as determined by HPLC, NMR, and other analytical techniques. Our quality commitment ensures traceability and consistency for your critical synthesis workflows.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). This compound may be hygroscopic (moisture-sensitive); therefore, the container must be kept tightly sealed under an inert atmosphere if specified. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.