Description

R-2-Isopropyl-Piperazine Dihydrochloride is a high-purity chiral piperazine derivative, a critical building block in modern organic synthesis. Its value lies in its role as a versatile intermediate for constructing complex molecules with defined stereochemistry, essential for developing active pharmaceutical ingredients (APIs). This compound is primarily needed by research institutions and pharmaceutical companies engaged in the discovery and process development of new therapeutic agents, particularly in areas requiring enantiomerically pure scaffolds.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the synthesis of novel drug candidates, especially in central nervous system (CNS) and antiviral research.
• Agrochemical Research: Used in the development of enantiomerically pure active ingredients for advanced crop protection agents.
• Ligand & Catalyst Development: Serves as a precursor for creating chiral ligands and organocatalysts used in asymmetric synthesis.
• Chemical Biology & Proteomics: Employed in the design and synthesis of molecular probes and tool compounds for biological target validation.
• Custom Synthesis & Contract Manufacturing: A requested intermediate for custom chemical synthesis services (CDMO) producing batches under cGMP for clinical trials.

Basic Information

Product Name	R-2-Isopropyl-Piperazine Dihydrochloride
CAS No.	1217663-39-2
Molecular Formula	C7H18Cl2N2
Molecular Weight	201.14 g/mol
Synonyms	(R)-2-Isopropylpiperazine Dihydrochloride; (R)-2-(1-Methylethyl)piperazine Dihydrochloride; (R)-2-Isopropylpiperazine Dihydrochloride Salt; (R)-2-(Propan-2-yl)piperazine Dihydrochloride; (2R)-2-(Propan-2-yl)piperazine-1,4-diium Dichloride; (R)-2-Isopropyl-piperazine Dihydrochloride; Piperazine, 2-(1-methylethyl)-, (2R)-, dihydrochloride
EINECS	Contact for details

Quality Control

Our R-2-Isopropyl-Piperazine Dihydrochloride is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity verification by HPLC, to ensure it meets the stringent requirements for pharmaceutical R&D and process chemistry. A detailed Certificate of Analysis (COA) providing batch-specific data for identity, purity, and chiral excess is supplied with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under an inert atmosphere after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥98.0%
Chiral Purity (HPLC)	≥99.0% ee
Water Content (KF)	≤1.0%
Residue on Ignition	≤0.1%
Heavy Metals	≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.