Description

(R)-1-Benzyl 2-Methyl Piperazine-1,2-Dicarboxylate is a high-purity chiral piperazine derivative, serving as a critical building block in advanced organic synthesis. Its enantiomerically pure structure is essential for developing pharmaceuticals with specific stereochemical requirements, ensuring high efficacy and reduced side effects. This compound is primarily needed by research institutions and pharmaceutical companies engaged in the development of active pharmaceutical ingredients (APIs), particularly for central nervous system (CNS) and antiviral therapies.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the synthesis of novel drug candidates, especially for neurological and psychiatric disorders.
• Asymmetric Catalyst Ligand Precursor: Used in the preparation of ligands for metal-catalyzed asymmetric reactions to create other enantiopure compounds.
• Protease Inhibitor Research: Serves as a core scaffold in the development of inhibitors targeting specific viral or human proteases.
• Chemical Biology & Medicinal Chemistry: Employed in structure-activity relationship (SAR) studies to optimize the potency and selectivity of lead molecules.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for scale-up and GMP production.
• Academic Research: Utilized in university and institutional labs for methodological development in synthetic organic chemistry.

Basic Information

Product Name	(R)-1-Benzyl 2-Methyl Piperazine-1,2-Dicarboxylate
CAS No.	1217598-28-1
Molecular Formula	C15H20N2O4
Molecular Weight	292.33 g/mol
Synonyms	1-Benzyl 2-methyl (2R)-piperazine-1,2-dicarboxylate; (R)-1-Benzyl 2-methyl piperazine-1,2-dicarboxylate; (R)-1-CBZ-2-Methyl Piperazine-1,2-Dicarboxylate; (R)-1-N-Carbobenzyloxy-2-N-Methoxycarbonylpiperazine; (2R)-1-[(Benzyloxy)carbonyl]-2-(methoxycarbonyl)piperazine; Benzyl (2R)-2-(methoxycarbonyl)piperazine-1-carboxylate; (R)-1-N-Cbz-2-N-Methyl Piperazine-1,2-Dicarboxylate
EINECS	Contact for details

Quality Control

Our (R)-1-Benzyl 2-Methyl Piperazine-1,2-Dicarboxylate is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high enantiomeric purity. We provide comprehensive analytical data, including HPLC for purity and chiral purity assessment. Certificates of Analysis (COA) detailing identity, assay, and impurity profiles are available for every batch upon request, supporting your regulatory and R&D documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from heat sources and incompatible materials. The compound is light-sensitive and should be handled under appropriate conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.