Description

(R)-2-Hydroxymethyl-Piperazine-2Hcl is a high-purity chiral piperazine derivative, serving as a critical building block in advanced organic synthesis. Its value lies in providing a stereochemically defined scaffold essential for creating complex molecules with specific biological activity. This compound is primarily needed by pharmaceutical R&D and fine chemical manufacturers for applications in drug discovery and the development of novel active pharmaceutical ingredients (APIs).

Application

• Pharmaceutical Intermediate: A key chiral synthon in the research and development of new therapeutic agents, particularly for central nervous system (CNS) and antiviral drugs.
• Asymmetric Synthesis: Used as a chiral auxiliary or ligand precursor in catalytic asymmetric reactions to induce stereoselectivity.
• Peptidomimetics & Bioactive Molecule Construction: Incorporated into the backbone of peptide mimics and other bioactive compounds to modulate their pharmacokinetic properties.
• Agrochemical Research: Employed in the synthesis of novel, enantiomerically pure pesticides and herbicides.
• Academic & Industrial R&D: Serves as a valuable reagent for methodological studies in organic chemistry and medicinal chemistry programs.

Basic Information

Product Name	(R)-2-Hydroxymethyl-Piperazine-2Hcl
CAS No.	1217482-26-2
Molecular Formula	C5H12N2O · 2HCl
Molecular Weight	209.09 g/mol
Synonyms	(R)-2-(Hydroxymethyl)piperazine dihydrochloride; (R)-Piperazine-2-methanol dihydrochloride; (2R)-2-Piperazinemethanol dihydrochloride; (R)-2-Hydroxymethylpiperazine Dihydrochloride; (R)-2-Piperazinylmethanol dihydrochloride; (R)-2-Methanolpiperazine dihydrochloride; (R)-HMP · 2HCl
EINECS	Contact for details

Quality Control

Our (R)-2-Hydroxymethyl-Piperazine-2Hcl is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity verification by HPLC, to ensure it meets the high standards required for pharmaceutical research. Certificates of Analysis (COA) with detailed specifications are provided for every shipment to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to minimize exposure to atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	< 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.