Description

(S)-1-Boc-2-Propylpiperazine Hydrochloride is a high-purity, chiral piperazine derivative used as a critical building block in advanced pharmaceutical synthesis. This compound is essential for medicinal chemistry research and development, particularly in the creation of novel active pharmaceutical ingredients (APIs) with specific stereochemical requirements. It is primarily utilized by pharmaceutical R&D laboratories, custom synthesis providers, and manufacturers of fine chemicals targeting neurological and oncological therapeutic areas.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the synthesis of complex drug molecules, especially those targeting central nervous system (CNS) disorders.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization for developing new therapeutic candidates.
• Asymmetric Synthesis: Serves as a chiral auxiliary or precursor in catalytic asymmetric reactions to introduce stereogenic centers.
• API Development: Incorporated into the backbone of potential Active Pharmaceutical Ingredients (APIs) requiring a specific (S)-configured piperazine moiety.
• Custom Synthesis & Contract Manufacturing: A valuable starting material for custom synthesis houses producing bespoke compounds for client drug discovery programs.
• Chemical Reference Standard: Can be supplied as a high-purity standard for analytical method development and quality control in pharmaceutical manufacturing.

Basic Information

Product Name	(S)-1-Boc-2-Propylpiperazine Hydrochloride
CAS No.	1217478-55-1
Molecular Formula	C12H25ClN2O2
Molecular Weight	264.79 g/mol
Synonyms	(S)-1-(tert-Butoxycarbonyl)-2-propylpiperazine hydrochloride; (S)-2-Propyl-1-Boc-piperazine hydrochloride; (S)-N-Boc-2-propylpiperazine HCl; (S)-1-Boc-2-propylpiperazine HCl; tert-Butyl (S)-2-propylpiperazine-1-carboxylate hydrochloride; (S)-1-(tert-Butyloxycarbonyl)-2-propylpiperazine hydrochloride; (S)-1-Boc-2-n-propylpiperazine hydrochloride
EINECS	Contact for details

Quality Control

Our (S)-1-Boc-2-Propylpiperazine Hydrochloride is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity verification by HPLC, to ensure it meets the high standards required for pharmaceutical R&D. A detailed Certificate of Analysis (COA) is provided with every shipment, confirming identity, purity, and impurity profiles. We adhere to cGMP guidelines where applicable to support our clients' regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and should be handled under a dry inert atmosphere to prevent degradation. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥98.0%
Chiral Purity (Chiral HPLC)	≥99.0% ee
Water Content (KF)	≤0.5%
Residue on Ignition	≤0.1%
Heavy Metals	≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.