Description

(R)-4-n-Boc-2-Propylpiperazine-Hcl CAS NO 1217468-71-7 is a high-purity chiral piperazine derivative, serving as a critical building block in modern pharmaceutical synthesis. This compound is valued for its role in constructing complex molecular architectures, particularly for active pharmaceutical ingredients (APIs) and advanced intermediates. It is primarily sought after by research institutions and manufacturers in the pharmaceutical and biotechnology sectors for the development of novel therapeutics.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the research and development of new drug candidates, particularly for central nervous system (CNS) and oncology targets.
• API Synthesis: Used in the multi-step synthesis of complex Active Pharmaceutical Ingredients (APIs) requiring a specific (R)-configured piperazine scaffold.
• Asymmetric Catalysis Research: Employed as a ligand precursor or a chiral auxiliary in academic and industrial research focused on asymmetric synthesis.
• Peptidomimetics Development: Integral for constructing peptidomimetic compounds, which mimic peptides but with enhanced metabolic stability and bioavailability.
• Chemical Biology Probes: Utilized in the design and synthesis of molecular probes for studying biological pathways and target engagement.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for custom synthesis projects under cGMP or research-grade conditions.

Basic Information

Item	Detail
Product Name	(R)-4-n-Boc-2-Propylpiperazine-Hcl
CAS No.	1217468-71-7
Molecular Formula	C12H25ClN2O2
Molecular Weight	264.79 g/mol
Synonyms	(R)-1-Boc-4-Propylpiperazine Hydrochloride; (R)-tert-Butyl 4-Propylpiperazine-1-carboxylate Hydrochloride; (R)-4-Propyl-1-(tert-butoxycarbonyl)piperazine Hydrochloride; (R)-N-Boc-4-Propylpiperazine HCl; (R)-1-(tert-Butoxycarbonyl)-4-propylpiperazine Hydrochloride; (R)-Boc-4-Propylpiperazine HCl; (R)-4-n-Propyl-1-Boc-piperazine Hydrochloride
EINECS	Contact for details

Quality Control

Our (R)-4-n-Boc-2-Propylpiperazine-Hcl is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity verification by HPLC, to ensure it meets the high standards required for pharmaceutical research and development. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment. We support development with research-grade material and can supply under cGMP guidelines for advanced clinical stage projects.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive); therefore, the container must be kept tightly sealed in a dry environment to prevent degradation. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥98.0%
Chiral Purity (Chiral HPLC)	≥99.0% ee
Water Content (KF)	≤0.5%
Residue on Ignition	≤0.1%
Heavy Metals	≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.