Description

(R)-1-n-Boc-2-Benzylpiperazine-Hcl is a high-purity chiral piperazine derivative, serving as a critical building block in advanced organic synthesis. Its value lies in providing a stereochemically defined scaffold for constructing complex molecules with precise biological activity. This intermediate is essential for research and development teams in the pharmaceutical and agrochemical industries, particularly those focused on creating novel active pharmaceutical ingredients (APIs) and fine chemicals.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the research and development of novel therapeutic agents, including central nervous system (CNS) drugs and receptor modulators.
• Asymmetric Synthesis: Used as a precursor or ligand in catalytic asymmetric reactions to introduce stereogenic centers with high enantiomeric purity.
• Peptidomimetics & Drug Discovery: Employed in the design and synthesis of peptidomimetic compounds and molecular libraries for high-throughput screening.
• Agrochemical Research: Serves as a building block for developing new chiral pesticides and herbicides with enhanced efficacy and selectivity.
• Academic & Contract Research: Utilized in university and CRO (Contract Research Organization) laboratories for methodological studies in synthetic organic chemistry.
• Custom Synthesis: A starting material for the custom manufacturing of more complex, proprietary chemical entities for client-specific projects.

Basic Information

Product Name	(R)-1-n-Boc-2-Benzylpiperazine-Hcl
CAS No.	1217466-36-8
Molecular Formula	C16H25ClN2O2
Molecular Weight	312.84 g/mol
Synonyms	(R)-1-Boc-2-Benzylpiperazine Hydrochloride; (R)-1-(tert-Butoxycarbonyl)-2-benzylpiperazine Hydrochloride; (R)-N-Boc-2-Benzylpiperazine HCl; (R)-2-Benzyl-1-(tert-butoxycarbonyl)piperazine Hydrochloride; tert-Butyl (R)-2-benzylpiperazine-1-carboxylate hydrochloride; (R)-1-Boc-2-Bn-piperazine HCl; (R)-1-N-Boc-2-Benzylpiperazine Hydrochloride Salt
EINECS	Contact for details

Quality Control

Our (R)-1-n-Boc-2-Benzylpiperazine-Hcl is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure high chemical and chiral purity, meeting the stringent requirements for pharmaceutical R&D. A comprehensive Certificate of Analysis (COA) detailing purity, enantiomeric excess, and impurity profiles is provided with every shipment to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and must be kept under an inert atmosphere (e.g., nitrogen or argon) for long-term storage to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Enantiomeric Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.