Description

(R)-2-Phenethyl-Piperazine is a chiral piperazine derivative of significant importance in advanced organic synthesis. This high-purity enantiomer serves as a critical building block for the development of novel pharmaceutical compounds, particularly those targeting the central nervous system. It is essential for research and manufacturing in the pharmaceutical, agrochemical, and fine chemical industries where stereochemical purity is paramount for biological activity.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the research and production of active pharmaceutical ingredients (APIs), especially for neurological and psychiatric therapeutics.
• Asymmetric Catalyst Ligand: Used in the synthesis of chiral ligands for metal-catalyzed asymmetric reactions, enhancing enantioselectivity.
• Agrochemical Research: Employed in the development of novel, enantiomerically pure pesticides and herbicides.
• Fine Chemical Synthesis: A versatile intermediate for creating complex, high-value specialty chemicals requiring specific stereochemistry.
• Academic & R&D: Serves as a standard or reagent in university and corporate research laboratories for methodological studies in organic and medicinal chemistry.

Basic Information

Product Name	(R)-2-Phenethyl-Piperazine
CAS No.	1217452-20-4
Molecular Formula	C12H18N2
Molecular Weight	190.29 g/mol
Synonyms	(R)-1-(2-Phenylethyl)piperazine; (R)-2-Phenylethylpiperazine; (R)-1-Phenethylpiperazine; (R)-N-Phenethylpiperazine; (R)-α-Phenethylpiperazine; (R)-PEP; (2R)-2-Phenethylpiperazine
EINECS	Contact for details

Quality Control

Our (R)-2-Phenethyl-Piperazine is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral HPLC for enantiomeric excess (ee) determination, to ensure it meets the high-purity standards required for pharmaceutical R&D and cGMP manufacturing. A detailed Certificate of Analysis (COA) is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent moisture absorption and degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals (as Pb)	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.