Description

(S)-4-n-Boc-2-Propylpiperazine-Hcl is a high-purity chiral piperazine derivative, a crucial building block in modern pharmaceutical synthesis. This compound matters as a key intermediate for constructing complex molecules, particularly in the development of active pharmaceutical ingredients (APIs) targeting the central nervous system and other therapeutic areas. Pharmaceutical R&D laboratories and fine chemical manufacturers need this material for its role in creating enantiomerically pure candidates during drug discovery and process development stages.

Application

• Pharmaceutical Intermediate: A critical chiral synthon in the synthesis of novel drug candidates, especially for neurological and psychiatric disorders.
• API Development: Used in the research and scale-up production of enantiomerically pure Active Pharmaceutical Ingredients (APIs).
• Asymmetric Synthesis: Serves as a versatile building block for introducing the (S)-configured piperazine moiety in complex molecular architectures.
• Medicinal Chemistry Research: Employed in structure-activity relationship (SAR) studies and lead optimization within drug discovery programs.
• Process Chemistry: Utilized in the development and optimization of scalable, GMP-compliant synthetic routes for pharmaceutical manufacturing.
• Custom Synthesis: A starting material for the contract manufacturing of specialized fine chemicals and advanced intermediates.

Basic Information

Item	Details
Product Name	(S)-4-n-Boc-2-Propylpiperazine-Hcl
CAS No.	1217448-65-1
Molecular Formula	C12H25ClN2O2
Molecular Weight	264.79 g/mol
Synonyms	(S)-1-Boc-4-Propylpiperazine-2-carboxylic acid hydrochloride; (S)-tert-Butyl 4-propylpiperazine-1-carboxylate hydrochloride; (S)-N-Boc-4-propylpiperazine hydrochloride; (S)-1-(tert-Butoxycarbonyl)-4-propylpiperazine hydrochloride; (2S)-1-(tert-Butoxycarbonyl)-4-propylpiperazin-1-ium chloride; (S)-4-Propyl-1-Boc-piperazine HCl; (S)-Boc-4-propylpiperazine HCl
EINECS	Contact for details

Quality Control

Our (S)-4-n-Boc-2-Propylpiperazine-Hcl is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity, suitable for demanding R&D and scale-up applications. We provide comprehensive analytical data, including chiral purity verification via HPLC. A Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is supplied with each batch to support your quality and regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under dry conditions to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥98.0%
Chiral Purity (HPLC)	≥99.0% ee
Water Content (KF)	≤1.0%
Residue on Ignition	≤0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.