Description

Doxercalciferol-D3 CAS NO 1217448-46-8 is a synthetic vitamin D analog and an active pharmaceutical ingredient (API). It is a critical compound for the development of therapeutic agents targeting conditions related to calcium and phosphate metabolism. This high-purity intermediate is essential for pharmaceutical manufacturers and research institutions focused on endocrinology and renal care.

Application

• Active Pharmaceutical Ingredient (API) in the synthesis of vitamin D-based therapeutics.
• Research & Development for studying calcium and phosphate homeostasis and related metabolic disorders.
• Precursor in the manufacture of specialized prodrugs targeting secondary hyperparathyroidism.
• Reference Standard for analytical method development and quality control in pharmaceutical laboratories.
• Biochemical Research for investigating vitamin D receptor (VDR) signaling pathways.

Basic Information

Product Name	Doxercalciferol-D3
CAS No.	1217448-46-8
Molecular Formula	C28H44O3
Molecular Weight	428.65 g/mol
Synonyms	1α-Hydroxyergocalciferol-D3; 1α-Hydroxyvitamin D2-D3; (5Z,7E)-(1S,3R)-9,10-Secocholesta-5,7,10(19)-triene-1,3-diol; Doxercalciferol D3 labeled; Doxercalciferol deuterated analog
EINECS	Contact for details

Quality Control

Our Doxercalciferol-D3 is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the stringent requirements for pharmaceutical intermediates. Certificates of Analysis (COA) are available upon request, detailing all relevant specifications.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) at a controlled room temperature (15-25°C) to prevent oxidation and degradation. Keep the container tightly sealed in a dry, cool, and well-ventilated place.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Residual Solvents (GC)	Complies with ICH guidelines
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.