Description

(S)-4-n-Boc-2-Ethylpiperazine-Hcl is a high-purity, chiral piperazine derivative used as a critical building block in advanced organic synthesis. This compound is essential for the development of novel active pharmaceutical ingredients (APIs), particularly in medicinal chemistry and drug discovery. It is primarily needed by research institutions and pharmaceutical manufacturers focused on creating enantiomerically pure compounds for therapeutic applications.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the synthesis of complex drug molecules, especially those targeting the central nervous system.
• Medicinal Chemistry Research: Used in the design and development of new chemical entities (NCEs) and lead optimization studies.
• Asymmetric Synthesis: Serves as a chiral auxiliary or precursor for constructing enantiomerically pure heterocyclic compounds.
• API Development: Integral in the multi-step synthesis of potential Active Pharmaceutical Ingredients (APIs) requiring specific stereochemistry.
• Chemical Biology Probes: Used to create tool compounds for studying biological pathways and protein-ligand interactions.
• Custom Synthesis: A starting material for contract research and manufacturing organizations (CROs/CMOs) producing bespoke compounds for clients.

Basic Information

Product Name	(S)-4-n-Boc-2-Ethylpiperazine-Hcl
CAS No.	1217446-30-4
Molecular Formula	C11H23ClN2O2
Molecular Weight	250.77 g/mol
Synonyms	(S)-1-tert-Butyl 4-ethyl 2-ethylpiperazine-1,4-dicarboxylate hydrochloride; (S)-1-Boc-2-ethylpiperazine hydrochloride; (S)-4-(tert-Butoxycarbonyl)-2-ethylpiperazine hydrochloride; (S)-N-Boc-2-ethylpiperazine HCl; tert-Butyl (S)-2-ethylpiperazine-1-carboxylate hydrochloride; (S)-2-Ethyl-1-Boc-piperazine hydrochloride; (S)-2-Ethylpiperazine-1-carboxylic acid tert-butyl ester hydrochloride
EINECS	Contact for details

Quality Control

Our (S)-4-n-Boc-2-Ethylpiperazine-Hcl is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure high chemical purity, correct stereochemistry, and compliance with research-grade standards. A comprehensive Certificate of Analysis (COA) detailing purity, chiral purity (enantiomeric excess), and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed in a dry environment to prevent moisture absorption and degradation. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.