Description

1-(4-Piperidinyl)-Piperazine Hydrochloride is a high-purity, heterocyclic organic compound supplied as a hydrochloride salt for enhanced stability and handling. This versatile building block is critical for pharmaceutical research and development, particularly in the synthesis of complex active pharmaceutical ingredients (APIs). It is primarily utilized by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and fine chemical industries seeking reliable, high-quality intermediates.

Application

• Pharmaceutical Intermediate: A key synthon in the research and production of novel drug candidates, particularly those targeting central nervous system (CNS) disorders.
• Chemical Synthesis Building Block: Used to construct complex piperazine- and piperidine-containing molecular frameworks in medicinal chemistry.
• Agrochemical Research: Serves as a precursor in the development of new pesticides and herbicides that require specific heterocyclic architectures.
• Ligand and Catalyst Development: Employed in the preparation of specialized ligands for catalysis and metal complexation studies.
• Academic and Contract Research: Essential for investigative chemistry in university laboratories and contract research organizations (CROs).
• Custom Synthesis Projects: A starting material for bespoke chemical synthesis services catering to specific client requirements.

Basic Information

Product Name	1-(4-Piperidinyl)-Piperazine Hydrochloride
CAS No.	1217074-64-0
Molecular Formula	C9H19N3·HCl
Molecular Weight	205.73 g/mol (Free base: 169.27 g/mol)
Synonyms	1-(Piperidin-4-yl)piperazine hydrochloride; 4-(Piperazin-1-yl)piperidine hydrochloride; 1-Piperidin-4-yl-piperazine hydrochloride; Piperazine, 1-(4-piperidinyl)-, hydrochloride; 4-Piperazin-1-ylpiperidine hydrochloride; 1-(4-Piperidyl)piperazine monohydrochloride
EINECS	Contact for details

Quality Control

Our 1-(4-Piperidinyl)-Piperazine Hydrochloride is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, identity confirmation by IR and NMR, and residual solvent analysis, to ensure it meets the high standards required for research and development. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting all critical quality attributes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed in a dry environment to prevent moisture absorption and potential degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.