Description

(S)-2-(5-Methylpyrazine-2-Carboxamido)Non-8-Enoic Acid is a high-purity, non-natural amino acid derivative featuring a terminal alkene group, designed for advanced pharmaceutical and biochemical research. This compound serves as a critical chiral building block for the synthesis of novel peptide-based therapeutics and enzyme inhibitors. It is primarily utilized by medicinal chemists and research scientists in the pharmaceutical, biotechnology, and agrochemical sectors for drug discovery and development programs.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the development of novel protease inhibitors and other peptide-mimetic drugs.
• Peptide Synthesis: Used in solid-phase and solution-phase peptide synthesis to incorporate a unique, functionalized side chain.
• Bioconjugation: The terminal alkene moiety enables site-specific modifications via click chemistry (e.g., thiol-ene reactions) for labeling or linker attachment.
• Medicinal Chemistry Research: Employed in structure-activity relationship (SAR) studies to explore new chemical entities for therapeutic targets.
• Chemical Biology Probes: Serves as a precursor for creating activity-based probes to study enzyme function and mechanism.
• Agrochemical Research: Potential intermediate in the synthesis of novel, bioactive compounds for crop protection.

Basic Information

Product Name	(S)-2-(5-Methylpyrazine-2-Carboxamido)Non-8-Enoic Acid
CAS No.	1216941-97-7
Molecular Formula	C₁₅H₂₃N₃O₃
Molecular Weight	293.36 g/mol
Synonyms	(2S)-2-[(5-Methylpyrazine-2-yl)formamido]non-8-enoic acid; (S)-2-((5-Methylpyrazine-2-carboxamido)non-8-enoic acid; 8-Nonenoic acid, 2-[[(5-methyl-2-pyrazinyl)carbonyl]amino]-, (2S)-; 5-Methylpyrazine-2-carboxylic acid (S)-8-nonenylamide; A chiral non-natural amino acid derivative; Terminal alkene functionalized amino acid.
EINECS	Contact for details

Quality Control

Our (S)-2-(5-Methylpyrazine-2-Carboxamido)Non-8-Enoic Acid is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity verification by HPLC, to ensure it meets the high standards required for research and development. A detailed Certificate of Analysis (COA) is provided with every shipment, confirming identity, purity, and specific parameters.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). For long-term storage under inert atmosphere, please contact our technical team for specific recommendations.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.