Description

5,6,7,8-Tetrahydroimidazo[1,2-A]Pyridine-3-Sulfonyl Chloride is a high-value, heterocyclic sulfonyl chloride derivative that serves as a critical building block in advanced organic synthesis. Its primary commercial value lies in its high reactivity, enabling the efficient introduction of the sulfonamide functional group into complex molecular architectures. This compound is essential for research and development chemists in the pharmaceutical and agrochemical industries, particularly for creating novel active ingredients and fine-tuning molecular properties.

Application

This versatile chemical intermediate is primarily utilized in the synthesis of complex molecules. Key application areas include:

• Pharmaceutical Intermediates: A key precursor in the synthesis of potential drug candidates, particularly those targeting central nervous system (CNS) disorders and other therapeutic areas.
• Agrochemical Synthesis: Used in the research and development of novel herbicides, fungicides, and insecticides, where the sulfonamide group is a common pharmacophore.
• Chemical Biology & Proteomics: Employed as a reactive handle for labeling proteins or modifying biomolecules in research applications.
• Material Science Research: Investigated as a monomer or cross-linking agent for creating novel polymers with specific functional properties.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for the production of client-specific target molecules.

Basic Information

Product Name	5,6,7,8-Tetrahydroimidazo[1,2-A]Pyridine-3-Sulfonyl Chloride
CAS No.	1216892-47-5
Molecular Formula	C7H9ClN2O2S
Molecular Weight	220.68 g/mol
Synonyms	Imidazo[1,2-a]pyridine-3-sulfonyl chloride, 5,6,7,8-tetrahydro-; 5,6,7,8-Tetrahydroimidazo[1,2-a]pyridine-3-sulfonyl chloride; Tetrahydroimidazopyridine sulfonyl chloride; 1216892-47-5; AI3-63535; ZINC000103249795; SCHEMBL23342297; DTXSID70731891
EINECS	Contact for details

Quality Control

Our production of 5,6,7,8-Tetrahydroimidazo[1,2-A]Pyridine-3-Sulfonyl Chloride adheres to stringent quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and mass spectrometry, to ensure high purity and consistent chemical identity. Certificates of Analysis (COA) detailing all specifications are provided with every shipment. We are committed to meeting the exacting standards required for pharmaceutical R&D and other critical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place. Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent decomposition. Recommended long-term storage temperature is 2-8°C. Keep away from strong acids and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white powder or crystalline solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.