Description

6-(5-Chloropyridin-2-Yl)-7-Oxo-6,7-Dihydro-5H-Pyrrolo[3,4-B]Pyrazin-5-Yl Piperazine-1-Carboxylate Hydrochloride is a high-purity, non-racemic pharmaceutical intermediate with a complex heterocyclic structure. This compound is critical for research and development in medicinal chemistry, particularly in the synthesis of targeted small-molecule therapeutics. It is primarily utilized by pharmaceutical R&D laboratories and fine chemical manufacturers engaged in the development of novel drug candidates.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of advanced drug candidates, particularly in kinase inhibitor research.
• Medicinal Chemistry R&D: Used for structure-activity relationship (SAR) studies and lead optimization in drug discovery programs.
• Biochemical Research: Serves as a reference standard or a probe compound in biological screening assays.
• Fine Chemical Synthesis: Employed in multi-step organic synthesis to construct complex molecular architectures for specialized applications.
• Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for cGMP production of active pharmaceutical ingredients (APIs).

Basic Information

Product Name	6-(5-Chloropyridin-2-Yl)-7-Oxo-6,7-Dihydro-5H-Pyrrolo[3,4-B]Pyrazin-5-Yl Piperazine-1-Carboxylate Hydrochloride
CAS No.	1216659-29-8
Molecular Formula	C17H16ClN5O3 • HCl
Molecular Weight	426.70 g/mol
Synonyms	6-(5-Chloropyridin-2-yl)-7-oxo-6,7-dihydro-5H-pyrrolo[3,4-b]pyrazin-5-yl piperazine-1-carboxylate hydrochloride; 6-(5-Chloro-2-pyridinyl)-7-oxo-6,7-dihydro-5H-pyrrolo[3,4-b]pyrazin-5-yl piperazine-1-carboxylate hydrochloride; (6-(5-Chloropyridin-2-yl)-7-oxo-5,6-dihydro-7H-pyrrolo[3,4-b]pyrazin-5-yl) piperazine-1-carboxylate hydrochloride; 1216659-29-8; UNII-6K8X2VQ8F8; 6K8X2VQ8F8
EINECS	Contact for details

Quality Control

Our production of 6-(5-Chloropyridin-2-Yl)-7-Oxo-6,7-Dihydro-5H-Pyrrolo[3,4-B]Pyrazin-5-Yl Piperazine-1-Carboxylate Hydrochloride adheres to stringent quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC for purity and chiral purity assessment, to ensure it meets the exacting standards required for pharmaceutical R&D. Certificates of Analysis (COA) with detailed chromatographic data are provided to guarantee traceability and compliance with your internal specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and should be handled under dry conditions to prevent degradation. For long-term storage, consider desiccants or an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference
Purity (HPLC)	≥ 98.0%
Chiral Purity	≥ 99.0% ee
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.