Description

5-Bromo-6-Morpholinonicotinicacid is a high-purity, advanced pharmaceutical intermediate characterized by its distinct heterocyclic structure. This compound is of significant value in medicinal chemistry for its role as a key building block in the synthesis of novel active pharmaceutical ingredients (APIs). It is primarily sought after by research institutions and pharmaceutical manufacturers engaged in the development of targeted therapies, particularly within oncology and central nervous system (CNS) drug discovery pipelines.

Application

• Pharmaceutical Intermediate: Serves as a critical precursor in the multi-step synthesis of complex drug candidates and novel chemical entities.
• Medicinal Chemistry Research: Used extensively in structure-activity relationship (SAR) studies and lead optimization for new therapeutic targets.
• Kinase Inhibitor Development: A valuable scaffold for constructing molecules designed to modulate kinase activity, relevant in oncology research.
• Contract Research & Manufacturing (CRO/CMO): Supplied to organizations providing custom synthesis and process development services.
• Academic Research: Utilized in university and institutional labs for exploring new heterocyclic chemistry and reaction methodologies.
• Chemical Reference Standard: Can be supplied as a high-purity standard for analytical method development and quality control.

Basic Information

Product Name	5-Bromo-6-Morpholinonicotinicacid
CAS No.	1216637-77-2
Molecular Formula	C10H11BrN2O3
Molecular Weight	287.11 g/mol
Synonyms	5-Bromo-6-morpholinopyridine-3-carboxylic acid; 3-Pyridinecarboxylic acid, 5-bromo-6-morpholino-; 5-Bromo-6-morpholin-4-ylnicotinic acid; 6-Morpholino-5-bromonicotinic acid; 5-Bromo-6-(morpholin-4-yl)nicotinic acid; 1216637-77-2; 5-Bromo-6-morpholinonicotinic acid
EINECS	Contact for details

Quality Control

Our 5-Bromo-6-Morpholinonicotinicacid is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. Each lot is subjected to rigorous analytical testing, including HPLC for purity determination and NMR/IR for structural confirmation. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a dry environment to prevent degradation. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.