Description

8-Bromo-[1,2,4]triazolo[4,3-a]pyridin-6-amine is a high-value heterocyclic building block featuring a fused triazolopyridine core with distinct bromine and amine functional groups. This compound matters for its role as a versatile intermediate in the synthesis of complex molecules, particularly in pharmaceutical research and development. It is primarily needed by medicinal chemists and process development scientists in the pharmaceutical, agrochemical, and advanced materials industries for constructing novel active compounds.

Application

• Pharmaceutical Intermediate: A key synthon for the development of new drug candidates, particularly in kinase inhibitor and central nervous system (CNS) active compound libraries.
• Agrochemical Research: Used in the synthesis of novel herbicides, fungicides, and insecticides, leveraging its heterocyclic structure for bioactivity.
• Material Science: Serves as a precursor for organic electronic materials, such as ligands for metal-organic frameworks (MOFs) or components for organic light-emitting diodes (OLEDs).
• Chemical Biology: Employed as a probe or tag in bioconjugation chemistry due to the reactivity of its bromine and amine groups.
• Academic & Contract Research: Utilized in university and CRO (Contract Research Organization) settings for methodological studies and the exploration of new chemical spaces.
• Custom Synthesis: A starting point for the contract manufacturing of specialized, high-value fine chemicals for client-specific projects.

Basic Information

Product Name	8-Bromo-[1,2,4]triazolo[4,3-a]pyridin-6-amine
CAS No.	1216212-82-6
Molecular Formula	C6H4BrN5
Molecular Weight	226.03 g/mol
Synonyms	8-Bromo-6-amino-[1,2,4]triazolo[4,3-a]pyridine; 6-Amino-8-bromo-[1,2,4]triazolo[4,3-a]pyridine; 8-Bromo-6-aminotriazolopyridine; 1216212-82-6; 8-Bromo-6-amino-1,2,4-triazolo[4,3-a]pyridine; 8-Bromo-1,2,4-triazolo[4,3-a]pyridin-6-amine
EINECS	Contact for details

Quality Control

Our 8-Bromo-[1,2,4]triazolo[4,3-a]pyridin-6-amine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and NMR for structural confirmation, to ensure compliance with exacting standards for research and development use. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is available for every shipment upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	Off-white to light yellow powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.