Description

7-tert-Butyl 3-Ethyl 5,6-Dihydro-[1,2,4]Triazolo[4,3-A]Pyrazine-3,7(8H)-Dicarboxylate is a high-purity, advanced pharmaceutical intermediate with the CAS registry number 1215852-11-1. This compound is valued for its role as a critical building block in the synthesis of complex heterocyclic molecules, particularly in medicinal chemistry. It is primarily sought after by research institutions and pharmaceutical companies engaged in the development of novel active pharmaceutical ingredients (APIs) and drug candidates.

Application

• Pharmaceutical Intermediate: Serves as a key precursor in the synthesis of complex drug molecules, particularly those targeting the central nervous system.
• Medicinal Chemistry Research: Used in lead optimization and structure-activity relationship (SAR) studies for new therapeutic agents.
• Heterocyclic Compound Synthesis: A versatile scaffold for constructing fused triazolopyrazine ring systems with potential biological activity.
• Contract Research & Development (CRO/CMO): Supplied to organizations specializing in custom synthesis and process development for clinical trial materials.
• Academic Research: Utilized in university and institutional labs for studying novel organic reactions and heterocyclic chemistry.
• API Development: Integral to the development and scale-up processes for new active pharmaceutical ingredients.

Basic Information

Product Name	7-tert-Butyl 3-Ethyl 5,6-Dihydro-[1,2,4]Triazolo[4,3-A]Pyrazine-3,7(8H)-Dicarboxylate
CAS No.	1215852-11-1
Molecular Formula	C15H22N4O4
Molecular Weight	322.36 g/mol
Synonyms	7-tert-Butyl 3-ethyl 5,6,7,8-tetrahydro-[1,2,4]triazolo[4,3-a]pyrazine-3,7-dicarboxylate; 3-Ethyl 7-(tert-butyl) 5,6-dihydro-[1,2,4]triazolo[4,3-a]pyrazine-3,7(8H)-dicarboxylate; tert-Butyl 3-ethyl 5,6-dihydro-1H,8H-[1,2,4]triazolo[4,3-a]pyrazine-3,7-dicarboxylate; 1,2,4-Triazolo[4,3-a]pyrazine-3,7(8H)-dicarboxylic acid, 5,6-dihydro-, 3-ethyl 7-(1,1-dimethylethyl) ester; CAS 1215852-11-1
EINECS	Contact for details

Quality Control

Our production of 7-tert-Butyl 3-Ethyl 5,6-Dihydro-[1,2,4]Triazolo[4,3-A]Pyrazine-3,7(8H)-Dicarboxylate adheres to stringent quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via NMR and mass spectrometry, to ensure it meets the high standards required for pharmaceutical R&D. Certificates of Analysis (COA) with detailed chromatographic data are provided for every shipment to guarantee traceability and consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). Keep away from strong bases and incompatible organic solvents. For long-term storage, consider inert gas purging to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Related Substances (HPLC)	Individual impurity ≤ 0.5%
Total Impurities	≤ 2.0%
Residual Solvents (GC)	Meets ICH Q3C guidelines
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.