Description

5-Bromo-2-Ethoxy-3-Nitro-4-Picoline is a high-purity, multi-functional heterocyclic building block of significant interest in advanced organic synthesis. Its unique molecular architecture, featuring bromo, ethoxy, and nitro substituents on a picoline core, makes it a versatile intermediate for constructing complex molecules. This compound is primarily utilized by research chemists and process development scientists in the pharmaceutical and agrochemical industries for the development of novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of new drug candidates, particularly for creating libraries of nitrogen-containing heterocycles with potential biological activity.
• Agrochemical Synthesis: Serves as a precursor in the design and synthesis of novel herbicides, fungicides, and insecticides, leveraging its halogen and nitro functional groups for structural diversification.
• Material Science Research: Used in the development of specialty chemicals, ligands for catalysis, and advanced organic electronic materials due to its electron-deficient aromatic system.
• Chemical Biology & Proteomics: Can be employed as a reactive handle or a tag in the synthesis of molecular probes for studying biological systems and protein interactions.
• Academic & Contract Research: An essential reagent for methodological studies in organic chemistry, enabling novel cross-coupling and functional group transformation reactions.

Basic Information

Product Name	5-Bromo-2-Ethoxy-3-Nitro-4-Picoline
CAS No.	1215206-58-8
Molecular Formula	C8H9BrN2O3
Molecular Weight	261.07 g/mol
Synonyms	5-Bromo-2-ethoxy-3-nitro-4-methylpyridine; 4-Picoline, 5-bromo-2-ethoxy-3-nitro-; 3-Nitro-5-bromo-2-ethoxy-4-methylpyridine; 2-Ethoxy-3-nitro-5-bromo-4-picoline; 5-Bromo-2-ethoxy-3-nitro-4-methylpyridine; 4-Methyl-5-bromo-2-ethoxy-3-nitropyridine
EINECS	Contact for details

Quality Control

Every batch of 5-Bromo-2-Ethoxy-3-Nitro-4-Picoline is manufactured under strict quality management protocols. We ensure compliance with high-purity standards suitable for research and development applications. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from heat sources and incompatible materials. Due to its light-sensitive nature, prolonged exposure to direct light should be avoided.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.