Description

1-(2-Pyridyl)Cyclopropylamine Dihydrochloride is a high-purity, advanced pharmaceutical intermediate and versatile organic building block. This compound is valued for its unique cyclopropylamine-pyridine hybrid structure, which is critical for modulating biological activity and physicochemical properties in drug discovery. It is primarily utilized by research institutions and pharmaceutical companies engaged in the development of novel therapeutic agents, particularly in medicinal chemistry and process R&D.

Application

• Pharmaceutical Intermediate: A key synthon in the synthesis of active pharmaceutical ingredients (APIs) targeting central nervous system (CNS) disorders, infectious diseases, and oncology.
• Medicinal Chemistry Research: Used as a versatile scaffold for structure-activity relationship (SAR) studies and lead optimization in drug discovery programs.
• Ligand Synthesis: Serves as a precursor for the preparation of specialized ligands in catalysis and metal-organic frameworks (MOFs).
• Chemical Biology Probes: Employed in the development of molecular probes for studying enzyme function and biological pathways.
• Agrochemical Research: Investigated as a building block for novel crop protection agents and pesticides.
• Academic & Industrial R&D: Utilized in organic synthesis methodologies and the development of new chemical entities.

Basic Information

Product Name	1-(2-Pyridyl)Cyclopropylamine Dihydrochloride
CAS No.	1215107-39-3
Molecular Formula	C8H12Cl2N2
Molecular Weight	207.10 g/mol
Synonyms	1-(Pyridin-2-yl)cyclopropanamine dihydrochloride; 2-(1-Aminocyclopropyl)pyridine dihydrochloride; 1-(2-Pyridinyl)cyclopropanamine dihydrochloride; Cyclopropyl(2-pyridyl)amine dihydrochloride; 1-Amino-1-(2-pyridyl)cyclopropane dihydrochloride; 2-Cyclopropylaminopyridine dihydrochloride; 1-(Pyrid-2-yl)cyclopropylamine dihydrochloride
EINECS	Contact for details

Quality Control

Our 1-(2-Pyridyl)Cyclopropylamine Dihydrochloride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical quality attributes. Our production adheres to cGMP principles where applicable, supporting its use in regulated research and development environments.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a dry environment to prevent degradation. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Purity (HPLC, Area %)	≥ 99.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.