Description

1-Phenyl-Piperazine-2-Carboxylic Acid is a high-purity, functionalized piperazine derivative that serves as a critical chiral building block in advanced organic synthesis. Its value lies in providing a versatile scaffold for constructing complex molecules with precise stereochemistry. This compound is essential for research and development chemists in the pharmaceutical and agrochemical industries, particularly for creating novel active ingredients and fine-tuning molecular properties.

Application

• Pharmaceutical Intermediate: A key chiral precursor in the synthesis of central nervous system (CNS) active drugs, potential enzyme inhibitors, and receptor modulators.
• Agrochemical Research: Used in developing novel pesticides and herbicides, where the phenyl-piperazine moiety can contribute to specific biological activity.
• Chemical Biology & Proteomics: Employed as a building block for designing molecular probes, peptide mimetics, and tool compounds for studying biological pathways.
• Asymmetric Catalysis Ligand Synthesis: Serves as a starting material for creating novel chiral ligands and catalysts used in enantioselective transformations.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs and research organizations for custom synthesis projects requiring high-fidelity chiral intermediates.

Basic Information

Product Name	1-Phenyl-Piperazine-2-Carboxylic Acid
CAS No.	1214833-66-5
Molecular Formula	C11H14N2O2
Molecular Weight	206.24 g/mol
Synonyms	1-Phenylpiperazine-2-carboxylic acid; (R/S)-1-Phenylpiperazine-2-carboxylic acid; 2-Carboxy-1-phenylpiperazine; 1-Phenyl-2-piperazinecarboxylic acid; 1-Phenylpiperazine-2-carboxylic acid (racemic); 1-Phenyl-1,4-diazepane-2-carboxylic acid; 1-Phenyl-2-carboxypiperazine; 1-Phenylpiperazine-2-carboxylate
EINECS	Contact for details

Quality Control

Our 1-Phenyl-Piperazine-2-Carboxylic Acid is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC for purity and chiral analysis, to ensure it meets the stringent requirements for advanced synthetic applications. A Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment to guarantee traceability and consistency for your critical R&D and production processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to prevent moisture absorption, which can affect stability and handling properties.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity	Contact for details
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.