Description

3-Chloro-2-Hydroxy-6-(Trifluoromethyl)Pyridine is a high-value, multi-functional heterocyclic building block characterized by its unique trifluoromethyl and chloro-substituted pyridine core. This compound is essential for advanced chemical synthesis, offering a versatile scaffold for introducing specific functional groups and modulating the physicochemical properties of target molecules. It is primarily sought after by research and development teams in the pharmaceutical and agrochemical industries for the creation of novel active ingredients and specialty materials.

Application

• Pharmaceutical Intermediate: A key synthon for the development of active pharmaceutical ingredients (APIs), particularly in medicinal chemistry programs targeting CNS disorders, anti-infectives, and oncology.
• Agrochemical Synthesis: Serves as a critical precursor in the manufacture of advanced herbicides, fungicides, and insecticides, where the trifluoromethyl group enhances biological activity and environmental stability.
• Ligand and Catalyst Development: Used in organometallic chemistry to create novel ligands for catalysis, leveraging the pyridine nitrogen for metal coordination.
• Material Science Research: Employed in the synthesis of functionalized polymers, liquid crystals, and organic electronic materials due to its electron-withdrawing substituents.
• Custom Synthesis and Contract Manufacturing: A vital starting material for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) serving global clients.

Basic Information

Product Name	3-Chloro-2-Hydroxy-6-(Trifluoromethyl)Pyridine
CAS No.	1214391-77-1
Molecular Formula	C6H3ClF3NO
Molecular Weight	197.54 g/mol
Synonyms	3-Chloro-6-(trifluoromethyl)pyridin-2-ol; 2-Hydroxy-3-chloro-6-(trifluoromethyl)pyridine; 3-Chloro-2-hydroxy-6-trifluoromethylpyridine; 6-(Trifluoromethyl)-3-chloropyridin-2-ol; 3-Chloro-6-(trifluoromethyl)-2-pyridinol; 2-Pyridinol, 3-chloro-6-(trifluoromethyl)-; 3-Chloro-2-pyridinol, 6-(trifluoromethyl)-
EINECS	Contact for details

Quality Control

Our 3-Chloro-2-Hydroxy-6-(Trifluoromethyl)Pyridine is manufactured under a strict quality management system. Every batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide full traceability and detailed Certificates of Analysis (COA) with each shipment. Our quality commitment aligns with cGMP principles for pharmaceutical intermediates and ISO standards for industrial chemical production.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). Keep away from strong acids, strong bases, and oxidizing agents. This material is moisture-sensitive (hygroscopic); ensure containers are kept tightly sealed to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.