Description

3-Phenyl-5-(Trifluoromethyl)-Pyridine-2-Carboxylic Acid is a high-value, multi-functional heterocyclic building block characterized by its pyridine core, carboxylic acid functionality, and trifluoromethyl and phenyl substituents. This compound is essential for advanced research and development, particularly in the synthesis of novel active pharmaceutical ingredients (APIs) and agrochemicals. It is primarily sought after by pharmaceutical, agrochemical, and specialty chemical manufacturers for creating compounds with enhanced biological activity and metabolic stability.

Application

• Pharmaceutical Intermediate: A key synthon for the development of small molecule drugs, especially kinase inhibitors and other targeted therapies.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and insecticides, where the trifluoromethyl group improves lipophilicity and bioavailability.
• Ligand and Catalyst Development: Serves as a precursor for creating novel ligands in organometallic chemistry and catalysis.
• Material Science Research: Employed in the synthesis of organic electronic materials and metal-organic frameworks (MOFs).
• Custom Synthesis & Contract Manufacturing: A critical starting material for custom synthesis projects and scale-up services in fine chemical production.

Basic Information

Product Name	3-Phenyl-5-(Trifluoromethyl)-Pyridine-2-Carboxylic Acid
CAS No.	1214390-26-7
Molecular Formula	C13H8F3NO2
Molecular Weight	267.21 g/mol
Synonyms	2-Pyridinecarboxylic acid, 3-phenyl-5-(trifluoromethyl)-; 3-Phenyl-5-(trifluoromethyl)picolinic acid; 5-(Trifluoromethyl)-3-phenylpyridine-2-carboxylic acid; 3-Phenyl-5-trifluoromethylpyridine-2-carboxylic acid; Phenyl(trifluoromethyl)pyridinecarboxylic acid; PTPCA; CAS 1214390-26-7
EINECS	Contact for details

Quality Control

Our production of 3-Phenyl-5-(Trifluoromethyl)-Pyridine-2-Carboxylic Acid adheres to stringent quality management protocols to ensure batch-to-batch consistency and high purity. Each lot is analyzed using advanced techniques including HPLC, NMR, and mass spectrometry. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). The product is light-sensitive (store away from light) and should be handled with appropriate precautions for chemicals soluble in strong acid/organic solvent.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.