Description

Methyl 2-Chloro-3-Methoxyisonicotinate is a high-purity pyridine derivative ester, serving as a critical advanced intermediate in modern synthetic chemistry. Its value lies in its functionalized isonicotinate core, which provides a versatile scaffold for constructing complex molecules, particularly in the pharmaceutical and agrochemical sectors. This compound is essential for researchers and manufacturers in fine chemical synthesis, process development, and the production of active pharmaceutical ingredients (APIs) and crop protection agents.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders and infectious diseases.
• Agrochemical Synthesis: Used in the development and production of next-generation herbicides and insecticides, leveraging its halogenated pyridine structure.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized ligands used in transition metal catalysis and asymmetric synthesis.
• Material Science Research: Employed in the synthesis of functionalized organic molecules for electronic materials and organic light-emitting diodes (OLEDs).
• Custom Synthesis and Contract Manufacturing: A vital starting material for custom synthesis projects and scale-up processes in CDMO (Contract Development and Manufacturing Organization) facilities.
• Academic and R&D Laboratories: Used in medicinal chemistry programs and methodological research to explore new chemical reactions and pathways.

Basic Information

Product Name	Methyl 2-Chloro-3-Methoxyisonicotinate
CAS No.	1214387-44-6
Molecular Formula	C8H8ClNO3
Molecular Weight	201.61 g/mol
Synonyms	2-Chloro-3-methoxyisonicotinic acid methyl ester; Methyl 2-chloro-3-methoxypyridine-4-carboxylate; 4-Pyridinecarboxylic acid, 2-chloro-3-methoxy-, methyl ester; 2-Chloro-3-methoxypyridine-4-carboxylic acid methyl ester; 3-Methoxy-2-chloroisonicotinic acid methyl ester
EINECS	Contact for details

Quality Control

Our Methyl 2-Chloro-3-Methoxyisonicotinate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity, GC for residual solvents, and NMR/IR for structural confirmation, to ensure it meets the high standards required for advanced synthetic applications. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment. We support cGMP compliance for pharmaceutical applications upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep the container tightly sealed in a dry environment to minimize exposure to moisture. Store away from incompatible materials such as strong bases and strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.