Description

Ethyl 3-Bromo-6-Hydroxypyridine-2-Carboxylate is a high-purity, multi-functional heterocyclic building block of significant value in advanced organic synthesis. This compound is essential for research and development chemists seeking to construct complex molecular architectures, particularly in the pharmaceutical and agrochemical sectors. Its unique bromo- and hydroxypyridine carboxylate structure makes it a versatile precursor for the synthesis of active pharmaceutical ingredients (APIs), ligands, and functional materials.

Application

• Pharmaceutical Intermediate: A key synthon for the development of novel drug candidates, particularly in kinase inhibitor and central nervous system (CNS) therapeutic research.
• Agrochemical Synthesis: Used in the research and production of advanced pesticides and herbicides, leveraging its halogenated pyridine core.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized chelating ligands used in catalysis and material science.
• Material Science Research: Employed in the synthesis of organic electronic materials and metal-organic frameworks (MOFs).
• Chemical Biology Probes: Useful for synthesizing labeled compounds and probes for biochemical and diagnostic applications.
• Custom Synthesis and Contract Manufacturing: A critical starting material for custom synthesis projects requiring functionalized pyridine derivatives.

Basic Information

Product Name	Ethyl 3-Bromo-6-Hydroxypyridine-2-Carboxylate
CAS No.	1214377-79-3
Molecular Formula	C8H8BrNO3
Molecular Weight	246.06 g/mol
Synonyms	Ethyl 3-bromo-6-hydroxypicolinate; 3-Bromo-6-hydroxy-2-pyridinecarboxylic acid ethyl ester; 2-Pyridinecarboxylic acid, 3-bromo-6-hydroxy-, ethyl ester; 6-Hydroxy-3-bromopicolinic acid ethyl ester; Ethyl 3-bromo-6-oxo-1,6-dihydropyridine-2-carboxylate; 3-Bromo-6-hydroxypyridine-2-carboxylic acid ethyl ester; Ethyl 3-bromo-6-hydroxypicolinate (CAS 1214377-79-3)
EINECS	Contact for details

Quality Control

Every batch of Ethyl 3-Bromo-6-Hydroxypyridine-2-Carboxylate is manufactured under strict quality management systems and undergoes rigorous analytical testing to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing specifications such as assay (HPLC), identity (IR, NMR), and impurity profiles. Our quality commitment aligns with cGMP principles for pharmaceutical intermediates, ensuring reliable supply for critical R&D and scale-up projects.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). The product is light-sensitive and should be handled and stored accordingly. Keep away from strong bases and incompatible materials. For long-term storage, consider inert atmosphere conditions to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥97.0%
Purity (HPLC, Area %)	≥98.0%
Loss on Drying	≤0.5%
Residue on Ignition	≤0.1%
Heavy Metals	≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.