Description

2-Chloro-6-(Difluoromethoxy)Pyridine is a high-purity, advanced pharmaceutical intermediate and versatile chemical building block. This compound is valued for its unique halogenated pyridine structure, which is critical for introducing specific functional groups in complex synthetic pathways. It is primarily sought after by research institutions and manufacturers in the agrochemical and pharmaceutical sectors for the development of novel active ingredients.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of active pharmaceutical ingredients (APIs), particularly for candidates targeting central nervous system (CNS) disorders and other therapeutic areas.
• Agrochemical Synthesis: Used in the research and production of modern pesticides, herbicides, and fungicides, where its difluoromethoxy and chloro substituents contribute to biological activity and metabolic stability.
• Chemical Research & Development: Serves as a versatile precursor in organic synthesis for creating novel heterocyclic compounds and functional materials in academic and industrial R&D labs.
• Ligand and Catalyst Preparation: Employed in the development of specialized ligands for metal-catalyzed coupling reactions, which are fundamental in fine chemical manufacturing.
• Material Science Applications: Investigated as a monomer or additive for creating specialty polymers with specific electronic or surface properties.

Basic Information

Product Name	2-Chloro-6-(Difluoromethoxy)Pyridine
CAS No.	1214377-45-3
Molecular Formula	C6H4ClF2NO
Molecular Weight	179.55 g/mol
Synonyms	2-Chloro-6-(difluoromethoxy)pyridine; 6-Chloro-2-(difluoromethoxy)pyridine; Pyridine, 2-chloro-6-(difluoromethoxy)-; 1214377-45-3; 2-(Difluoromethoxy)-6-chloropyridine
EINECS	Contact for details

Quality Control

Our 2-Chloro-6-(Difluoromethoxy)Pyridine is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high chemical purity and consistency. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from strong bases and reducing agents. For long-term storage, consider under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.