Description

Ethyl 2-Bromo-6-Chloronicotinate is a high-purity, multi-functional heterocyclic building block essential for advanced organic synthesis. This compound is valued for its reactivity as a key intermediate in the development of complex molecules, particularly in pharmaceutical and agrochemical research. It is primarily sought after by R&D chemists and process development scientists in the fine chemical, pharmaceutical, and crop protection industries for constructing novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A crucial precursor in the synthesis of novel drug candidates, particularly for kinase inhibitors and other small molecule therapeutics.
• Agrochemical Synthesis: Used in the research and development of next-generation pesticides and herbicides, leveraging its halogenated pyridine core.
• Material Science Research: Serves as a building block for creating functional organic materials, such as ligands for catalysts or components in organic electronics.
• Chemical Biology Probes: Employed in the design and synthesis of molecular probes for studying biological pathways and target engagement.
• Custom Synthesis & Contract Manufacturing: A key starting material for custom synthesis projects and scale-up processes in CDMO (Contract Development and Manufacturing Organization) facilities.

Basic Information

Product Name	Ethyl 2-Bromo-6-Chloronicotinate
CAS No.	1214377-13-5
Molecular Formula	C8H7BrClNO2
Molecular Weight	264.50 g/mol
Synonyms	Ethyl 2-bromo-6-chloropyridine-3-carboxylate; 2-Bromo-6-chloronicotinic acid ethyl ester; 3-Pyridinecarboxylic acid, 2-bromo-6-chloro-, ethyl ester; 6-Chloro-2-bromonicotinic acid ethyl ester; 1214377-13-5; Ethyl 6-chloro-2-bromonicotinate
EINECS	Contact for details

Quality Control

Our Ethyl 2-Bromo-6-Chloronicotinate is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high purity and batch-to-batch consistency suitable for research and development applications. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.