Description

4-(4-Fluoro-3-Methylphenyl)Pyridine is a high-purity, advanced pharmaceutical intermediate characterized by its distinct biphenyl-pyridine structure. This compound is critical for the research and development of novel active pharmaceutical ingredients (APIs), particularly in therapeutic areas requiring targeted molecular scaffolds. It is primarily utilized by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries seeking to innovate within their synthesis pipelines.

Application

• Pharmaceutical Intermediate: Serves as a key building block in the synthesis of complex drug candidates, especially those targeting central nervous system (CNS) disorders and oncology.
• Agrochemical Research: Used in the development of new-generation herbicides and pesticides, leveraging its fluorinated aromatic system for enhanced bioactivity.
• Ligand Synthesis: Acts as a precursor for creating specialized ligands in catalytic systems and metal-organic frameworks (MOFs).
• Material Science: Employed in the research of organic electronic materials and photoactive compounds due to its conjugated system.
• Chemical Biology Probes: Utilized as a core structure for developing fluorescent tags and molecular probes for diagnostic applications.
• Custom Synthesis & Contract Manufacturing: A vital starting material for custom synthesis projects and scale-up processes under cGMP conditions.

Basic Information

Product Name	4-(4-Fluoro-3-Methylphenyl)Pyridine
CAS No.	1214354-05-8
Molecular Formula	C12H10FN
Molecular Weight	187.22 g/mol
Synonyms	4-(4-Fluoro-3-methylphenyl)pyridine; 4-(4-Fluoro-m-tolyl)pyridine; 4-(3-Methyl-4-fluorophenyl)pyridine; 4-(4-Fluoro-3-methylphenyl)pyridine; Pyridine, 4-(4-fluoro-3-methylphenyl)-; 1214354-05-8
EINECS	Contact for details

Quality Control

Our 4-(4-Fluoro-3-Methylphenyl)Pyridine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical specifications. Our quality commitment aligns with ICH guidelines and supports development from research to commercial scale.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep away from strong oxidizing agents and incompatible materials. For long-term storage, consider an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Any single impurity	≤ 0.5%
Residual Solvents (GC)	Complies with ICH Q3C
Loss on Drying	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.