Description

3-Fluoro-6-(Trifluoromethyl)Pyridine-2-Carbonitrile is a high-value, multi-functional heterocyclic building block characterized by its unique combination of fluorine atoms and a nitrile group. This molecular architecture is critical for modulating the physicochemical properties of advanced materials and active pharmaceutical ingredients, offering enhanced metabolic stability, lipophilicity, and bioavailability. It is an essential intermediate for researchers and manufacturers in the agrochemical and pharmaceutical sectors, where precise molecular engineering is required for developing novel crop protection agents and therapeutic compounds. The compound, identified by CAS number 1214348-68-1, is supplied to meet the stringent demands of industrial-scale synthesis and R&D applications.

Application

• Agrochemical Intermediate: A key synthon for the development of next-generation herbicides, fungicides, and insecticides, leveraging the fluorine motif for improved efficacy and environmental profile.
• Pharmaceutical Building Block: Used in the synthesis of active pharmaceutical ingredients (APIs), particularly in medicinal chemistry for creating molecules with optimized pharmacokinetic properties.
• Material Science Research: Serves as a precursor for functionalized pyridine derivatives used in the development of advanced polymers, liquid crystals, and electronic materials.
• Chemical Synthesis Reagent: Employed in cross-coupling reactions and as a versatile intermediate for introducing the trifluoromethylpyridine moiety into complex molecular frameworks.
• Life Sciences & Biotechnology: Utilized in the design and synthesis of molecular probes, diagnostic agents, and biochemical tools.

Basic Information

Product Name	3-Fluoro-6-(Trifluoromethyl)Pyridine-2-Carbonitrile
CAS No.	1214348-68-1
Molecular Formula	C7H2F4N2
Molecular Weight	190.10 g/mol
Synonyms	2-Cyano-3-fluoro-6-(trifluoromethyl)pyridine; 3-Fluoro-6-(trifluoromethyl)picolinonitrile; 3-Fluoro-6-trifluoromethyl-2-pyridinecarbonitrile; 6-(Trifluoromethyl)-3-fluoropyridine-2-carbonitrile; 2-Pyridinecarbonitrile, 3-fluoro-6-(trifluoromethyl)-; 3-Fluoro-6-trifluoromethylpyridine-2-carbonitrile
EINECS	Contact for details

Quality Control

Our 3-Fluoro-6-(Trifluoromethyl)Pyridine-2-Carbonitrile is manufactured under a strict quality management system. Each batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and MS, to ensure high purity and batch-to-batch consistency suitable for demanding synthetic applications. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting identity, purity, and impurity profiles. We adhere to cGMP principles where applicable to support our clients' regulatory and quality assurance requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). This compound is sensitive to strong alkali and should be kept away from incompatible materials. For long-term storage, consider using an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.