Description

Methyl 2-Bromo-6-Fluoroisonicotinate is a high-purity, multi-functional heterocyclic building block essential for advanced organic synthesis. This compound matters as a key intermediate in the development of complex molecules, particularly in the pharmaceutical and agrochemical sectors, where its unique halogenated pyridine structure enables critical bond-forming reactions. It is primarily needed by R&D chemists and process development scientists working on active pharmaceutical ingredients (APIs), crop protection agents, and novel materials.

Application

• Pharmaceutical Intermediate: A crucial precursor in the synthesis of novel drug candidates, particularly kinase inhibitors and other small-molecule therapeutics.
• Agrochemical Synthesis: Used in the research and development of next-generation herbicides, fungicides, and insecticides.
• Ligand and Catalyst Development: Serves as a starting material for creating specialized ligands used in transition metal catalysis.
• Material Science Research: Employed in the synthesis of functionalized organic molecules for electronic or photonic materials.
• Cross-Coupling Reactions: The bromo and fluoro substituents make it an excellent substrate for Suzuki, Stille, and other palladium-catalyzed cross-coupling reactions.
• Custom Synthesis and Contract Manufacturing: A valuable building block for custom synthesis houses serving the life sciences industry.

Basic Information

Item	Details
Product Name	Methyl 2-Bromo-6-Fluoroisonicotinate
CAS No.	1214345-88-6
Molecular Formula	C7H5BrFNO2
Molecular Weight	234.02 g/mol
Synonyms	Methyl 2-bromo-6-fluoropyridine-4-carboxylate; 2-Bromo-6-fluoro-isonicotinic acid methyl ester; 4-Pyridinecarboxylic acid, 2-bromo-6-fluoro-, methyl ester; Methyl 2-bromo-6-fluoropyridine-4-carboxylate; 2-Bromo-6-fluoropyridine-4-carboxylic acid methyl ester; Methyl 2-bromo-6-fluoro-4-pyridinecarboxylate
EINECS	Contact for details

Quality Control

Our Methyl 2-Bromo-6-Fluoroisonicotinate is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with each shipment to guarantee compliance with your research and development requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). Keep away from incompatible materials such as strong bases and reducing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.