Description

2-(5-Hydroxypyridin-2-Yl)Acetic Acid CAS NO 1214345-48-8 is a versatile pyridine derivative carboxylic acid, serving as a key synthetic intermediate in advanced organic chemistry. Its bifunctional structure, featuring both a phenolic hydroxyl and a carboxylic acid group on the pyridine ring, makes it a valuable building block for constructing complex molecular architectures. This compound is primarily utilized by research chemists and process development scientists in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A crucial building block for the synthesis of novel drug candidates, particularly in developing kinase inhibitors, anti-inflammatory agents, and other small molecule therapeutics.
• Agrochemical Synthesis: Used in the research and development of new herbicides, fungicides, and plant growth regulators, leveraging its heterocyclic core for bioactivity.
• Ligand and Chelator Precursor: The hydroxyl and carboxylic acid groups make it an excellent starting material for synthesizing polydentate ligands used in catalysis and metal complexation.
• Material Science Research: Employed in the development of functional organic materials, such as metal-organic frameworks (MOFs) or organic semiconductors, due to its rigid, planar structure and coordinating sites.
• Chemical Biology Probes: Serves as a scaffold for creating fluorescent tags, affinity probes, or other tools for studying biological systems and enzyme activity.

Basic Information

Product Name	2-(5-Hydroxypyridin-2-Yl)Acetic Acid
CAS No.	1214345-48-8
Molecular Formula	C7H7NO3
Molecular Weight	153.14 g/mol
Synonyms	2-(5-Hydroxy-2-pyridinyl)acetic acid; 2-(5-Hydroxypyridin-2-yl)ethanoic acid; 5-Hydroxypicolinic acid derivative; (5-Hydroxy-2-pyridyl)acetic acid; 2-Carboxymethyl-5-hydroxypyridine; 2-Pyridineacetic acid, 5-hydroxy-; 1214345-48-8
EINECS	Contact for details

Quality Control

Our 2-(5-Hydroxypyridin-2-Yl)Acetic Acid is produced under a strict quality management system. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and residual solvent analysis. A detailed Certificate of Analysis (COA) is provided with every shipment, ensuring traceability, consistency, and compliance with your research or development specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under inert atmosphere or in a desiccator for long-term storage to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.