Description

2,5-Dibromonicotinonitrile is a versatile brominated pyridine derivative, a key building block in advanced organic synthesis. This high-purity intermediate is critical for constructing complex molecular architectures, particularly in the development of active pharmaceutical ingredients (APIs) and functional agrochemicals. It is essential for research and production in pharmaceutical, agrochemical, and material science industries where precise halogenation is required.

Application

• Pharmaceutical Intermediate: A crucial precursor in the synthesis of novel drug candidates, especially kinase inhibitors and other nitrogen-containing heterocycles.
• Agrochemical Synthesis: Used in the development of new-generation herbicides, fungicides, and insecticides that require a brominated nicotinonitrile core.
• Material Science Research: Serves as a building block for creating functional organic materials, such as ligands for metal-organic frameworks (MOFs) or organic semiconductors.
• Cross-Coupling Reactions: An excellent substrate for palladium-catalyzed reactions like Suzuki, Stille, or Buchwald-Hartwig amination, enabling diverse carbon-carbon and carbon-heteroatom bond formations.
• Chemical Biology Probes: Utilized in the design and synthesis of molecular probes for studying biological processes and target engagement.

Basic Information

Product Name	2,5-Dibromonicotinonitrile
CAS No.	1214340-41-6
Molecular Formula	C6H2Br2N2
Molecular Weight	261.90 g/mol
Synonyms	2,5-Dibromo-3-cyanopyridine; 3-Cyano-2,5-dibromopyridine; Nicotinonitrile, 2,5-dibromo-; 2,5-Dibromopyridine-3-carbonitrile; Pyridine-3-carbonitrile, 2,5-dibromo-
EINECS	Contact for details

Quality Control

Our 2,5-Dibromonicotinonitrile is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and GC-MS, to ensure high chemical purity and identity confirmation. We provide detailed Certificates of Analysis (COA) with every shipment, guaranteeing traceability and compliance with your research or production specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.