Description

2-Pyridinecarboxylic Acid, 5-Chloro-6-Fluoro-, Methyl Ester is a high-purity, multi-functional heterocyclic building block of significant importance in advanced organic synthesis. Its core value lies in its precise molecular architecture, featuring both chloro and fluoro substituents, which enables the efficient construction of complex pharmacophores and agrochemical intermediates. This compound is essential for research and development chemists in the pharmaceutical and agrochemical industries, where it serves as a critical precursor for active ingredients and novel chemical entities.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of active pharmaceutical ingredients (APIs), particularly for compounds targeting central nervous system (CNS) disorders, anti-infectives, and oncology.
• Agrochemical Synthesis: Used in the development of novel herbicides, fungicides, and insecticides, where the halogenated pyridine core contributes to biological activity and environmental stability.
• Material Science Research: Serves as a monomer or functionalizing agent in the development of advanced polymers, ligands for catalysis, and organic electronic materials.
• Chemical Biology & Proteomics: Employed as a scaffold for designing molecular probes, enzyme inhibitors, and tags for studying biological systems.
• Custom Synthesis & Contract Manufacturing: A vital starting material for custom synthesis projects and scale-up processes in fine chemical production.

Basic Information

Product Name	2-Pyridinecarboxylic Acid, 5-Chloro-6-Fluoro-, Methyl Ester
CAS No.	1214335-09-7
Molecular Formula	C8H5ClFNO2
Molecular Weight	201.58 g/mol
Synonyms	Methyl 5-Chloro-6-fluoropyridine-2-carboxylate; 5-Chloro-6-fluoro-2-pyridinecarboxylic acid methyl ester; 5-Chloro-6-fluoropicolinic acid methyl ester; Methyl 5-chloro-6-fluoropicolinate; 2-Pyridinecarboxylic acid, 5-chloro-6-fluoro-, methyl ester; 5-Chloro-6-fluoropyridine-2-carboxylic acid methyl ester
EINECS	Contact for details

Quality Control

Our 2-Pyridinecarboxylic Acid, 5-Chloro-6-Fluoro-, Methyl Ester is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specification parameters. Our quality commitment aligns with cGMP principles for pharmaceutical intermediates, ensuring reliability for your most critical synthesis steps.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). This compound is sensitive to strong alkalis and fluorides; keep away from incompatible materials. For long-term storage, consider under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Assay (HPLC)	≥98.0%
Related Substances (HPLC)	Total impurities ≤2.0%
Residual Solvents (GC)	Complies with ICH Q3C guidelines
Water Content (KF)	≤0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.